Recombinant Human BAFFR/TNFRSF13C Protein

Name: Recombinant Human BAFFR/TNFRSF13C Protein
Brand: Novus Biologicals
SKU: NBP2-34879

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-34879

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Product Datasheet / COA

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Product Specifications
Scientific Data
Preparation & Storage
Background
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Specific Notices

Key Product Details

Source

E. coli

Accession #

Q96RJ3

Conjugate

Unconjugated

Applications

Bioactivity, SDS-PAGE

View all BAFFR/TNFRSF13C Proteins and Enzymes »

Product Specifications

Description

A single non-glycosylated polypeptide chain containing 76 amino acids corresponding to BAFFR/TNFRSF13C Source: E. coli

Uniprot ID: Q96RJ3

Amino Acid Sequence: MRRGPRSLRG RDAPAPTPCV PAECFDLLVR HCVACGLLRT PRPKPAGASS PAPRTALQPQ ESVGAGAGEA ALPLPG

Purity

>95%, by reducing SDS-PAGE

Endotoxin Level

Less than 1 EU/ug of BAFFR/TNFRSF13C as determined by LAL method.

Predicted Molecular Mass

7.8 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Activity

BAFF Receptor protein is fully biologically active when compared to standard. The ED50 as determined by its ability to block BAFF induced mouse splenocyte survival is 1.0-5.0 ug/ml in the presence of 1.0 ug/ml of rHuBAFF.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human BAFFR/TNFRSF13C Protein

SDS-Page: Recombinant Human BAFFR/TNFRSF13C Protein [NBP2-34879]

Formulation, Preparation and Storage

NBP2-34879

Formulation	Lyophilized from a 0.2 um filtered concentrated solution in 20 mM PB, pH 8.0, 500 mM NaCl.
Preservative	No Preservative
Concentration	Lyoph
Reconstitution	Recommended to centrifuge prior to opening. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/mL.
Format	Carrier-Free
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at -20 to -70C as supplied. After reconstitution, store at 2 to 8C for 1 month and at -20 to -70C for long term storage. Avoid repeated freeze-thaw cycles.

Background: BAFFR/TNFRSF13C

B Cell Activating Factor Receptor (BAFF-R), also named tumor necrosis factor receptor superfamily member 13C, is a member of the TNFR superfamily. It is highly expressed in spleen, lymph node, and resting B cells and to some extent in activated B cells, resting CD4+ cells and peripheral blood leukocytes. BAFF receptor is a type III transmembrane protein containing a single extracellular phenylalanine-rich domain and binds with high specificity to BAFF (TNFSF13B). It enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. BAFF receptor/BAFF signaling plays a critical role in B cell survival and maturation.

Long Name

B cell Activating Factor Receptor

Alternate Names

BAFF R, BR3, CD268, TNFRSF13C, BAFF Receptor/TNFRSF13C

Gene Symbol

TNFRSF13C

UniProt