Recombinant Human BCL-W/BCL2L2 Protein

Name: Recombinant Human BCL-W/BCL2L2 Protein
Brand: Novus Biologicals
SKU: NBP2-34895

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-34895

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Key Product Details

Source

E. coli

Accession #

Q92843

Conjugate

Unconjugated

Applications

SDS-PAGE

View all Bcl-w Proteins and Enzymes »

Product Specifications

Description

A single non-glycosylated polypeptide chain containing 171 amino acids corresponding to BCL-W/BCL2L2 Source: E. coli

Uniprot ID: Q92843

Amino Acid Sequence: ATPASAPDTR ALVADFVGYK LRQKGYVCGA GPGEGPAADP LHQAMRAAGD EFETRFRRTF SDLAAQLHVT PGSAQQRFTQ VSDELFQGGP NWGRLVAFFV FGAALCAESV NKEMEPLVGQ VQEWMVAYLE TQLADWIHSS GGWAEFTALY GDGALEEARR LREGNWASVR T

Purity

>95%, by SDS-PAGE and HPLC

Endotoxin Level

Less than 1 EU/ug of BCL-W/BCL2L2 as determined by LAL method.

Predicted Molecular Mass

18.6 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Activity

Test in Process.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human BCL-W/BCL2L2 Protein

SDS-PAGE: Recombinant Human BCL-W/BCL2L2 Protein [NBP2-34895]

SDS-Page: Human BCL-W/BCL2L2 Protein [NBP2-34895]

Formulation, Preparation and Storage

NBP2-34895

Formulation	0.2 um filtered concentrated solution in 25 mM Hepes, pH 7.4, 100 mM KCl, 10 % Glycerol, 0.02 % Tween-80.
Preservative	5% Trehalose
Concentration	Please see the vial label for concentration. If unlisted please contact technical services.
Format	Carrier-Free
Shipping	The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at -20C. Avoid freeze-thaw cycles.

Background: Bcl-w

BCL2L2, also named as Bcl-w, belongs to the Bcl-2 family and is encoded by the BCL2L2 gene in human. BCL2L2 (Bcl-w) is expressed in a wide range of tissues with highest levels in brain, spinal cord, testis, pancreas, heart, spleen and mammary glands, and moderate levels in thymus, ovary and small intestine. It is also expressed in cell lines of myeloid, fibroblast and epithelial origin. BCL2L2 (Bcl-w) is an anti-apoptotic (pro-survival) protein that reduces cell apoptosis under cytotoxic conditions. Mature human BCL2L2 (Bcl-w) shares 98 % - 99 % amino acid sequence identity with murine, bovine, canine Bcl-w.

Long Name

B Cell Lymphoma/Leukemia w

Alternate Names

BCL2L2, Bclw

Gene Symbol

BCL2L2

UniProt