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CCDC88B Recombinant Protein Antigen

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-88350PEP

Novus Biologicals, part of Bio-Techne
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NBP1-88350PEP

Key Product Details

Source

E. coli

Tag

N-terminal His6ABP (ABP = Albumin Binding Protein derived from Streptococcal Protein G)

Conjugate

Unconjugated

Applications

Antibody Competition

Product Specifications

Description

A recombinant protein antigen with a N-terminal His6-ABP tag corresponding to human CCDC88B.

Source: E. coli

Amino Acid Sequence: GLRQEGPEHKPGPSEPSSVQLEEQEGPNQGLDLATGQAEAREHDQRLEGTVRDPAWQKPQQKSEGALEVQVWEGPIPGESLASGVAEQEALREEVAQLRRKAEALGDELEAQARKLEAQNTEAARLSKELAQ

Fusion Tag: N-terminal His6ABP (ABP = Albumin Binding Protein derived from Streptococcal Protein G)

This product is intended to be used as a blocking antigen for antibody competition assays. Any other use of this antigen is done at the risk of the user. The use of this product for commercial production is strictly prohibited. Please contact technical support if you have any questions.

Purity

>80% by SDS-PAGE and Coomassie blue staining

Predicted Molecular Mass

32 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Applications

Antibody Competition (10 - 100 molar excess)

Application Notes

This recombinant antigen is only intended to be used as a blocking agent to confirm antibody specificity with the corresponding antibody, catalog number NBP1-88350.

It is purified by IMAC chromatography, and the expected concentration is greater than 0.5 mg/ml.

For current lot information, including availability, please contact our technical support team click nb-technical@bio-techne.com

Protein / Peptide Type

Recombinant Protein Antigen

Formulation, Preparation and Storage

NBP1-88350PEP
Formulation PBS and 1M Urea, pH 7.4.
Preservative No Preservative
Concentration Please see the vial label for concentration. If unlisted please contact technical services.
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at -20C. Avoid freeze-thaw cycles.

Background: CCDC88B

CCDC88B, also known as Coiled-coil domain-containing protein 88B, has 6 isoforms, a 1476 amino acid isoform that is 165 kDa, a 1034 amino acid isoform that is 114 kDa, a 621 amino acid isoform that is 67 kDa, a 1358 amino acid isoform that is 151 kDa, 696 amino acid isoform that is 79 kDa, and a 139 amino acid isoform that is 15 kDa; and may be involved in linking organelles to microtubules. This protein has been associated with LPS-induced acute lung injury, cerulein induced chronic pancreatitis, Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema, and Smith-Lemli-Opitz syndrome. CCDC88B interacts with PLEKHA5, PBX2, MAP3K7 and GRP78 in signaling pathways.

Alternate Names

78 kDa glucose-regulated protein GRP78-interacting protein induced by ER stress, brain leucine zipper domain-containing protein, brain leucine zipper protein, CCDC88, coiled-coil domain containing 88B, coiled-coil domain-containing protein 88B, gipie, HKRP3, hook-related protein 3

Gene Symbol

CCDC88B

Additional CCDC88B Products

Product Documents for CCDC88B Recombinant Protein Antigen

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for CCDC88B Recombinant Protein Antigen

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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