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Recombinant Human CCL23/Ck beta 8-1/MIP3 Protein

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-35021

Novus Biologicals, part of Bio-Techne
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NBP2-35021-100ug
NBP2-35021-1mg
NBP2-35021-500ug
NBP2-35021-5ug

Key Product Details

Source

E. coli

Accession #

Conjugate

Unconjugated

Applications

Bioactivity, SDS-PAGE

Product Specifications

Description

A single, non-glycosylated polypeptide chain containing 99 amino acids corresponding to CCL23/Ck beta 8-1/MIP3 Source: E. coli

Uniprot ID: P55773

Amino Acid Sequence: RVTKDAETEF MMSKLPLENP VLLDRFHATS ADCCISYTPR SIPCSLLESY FETNSECSKP GVIFLTKKGR RFCANPSDKQ VQVCMRMLKL DTRIKTRKN

This lyophilized preparation is stable at 2-8 degrees C, but should be kept at -20 degrees C for long term storage, preferably desiccated. Upon reconstitution, the preparation is most stable at -20 to -80 degrees C, and can be stored for one week at 2-8 degrees C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 degrees C to -80 degrees C. Avoid repeated freeze/thaw cycles.

Purity

> 97 % pure by SDS-PAGE and HPLC

Endotoxin Level

Less than 1 EU/ug of CCL23/Ck beta 8-1/MIP3 as determined by LAL method.

Predicted Molecular Mass

11.4 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Activity

Macrophage Inflammatory Protein 3 Protein is fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human T-lymphocytes is in a concentration of 10-50 ng/ml.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human CCL23/Ck beta 8-1/MIP3 Protein

SDS-PAGE: Recombinant Human CCL23/Ck beta 8-1/MIP3 Protein [NBP2-35021]

SDS-PAGE: Recombinant Human CCL23/Ck beta 8-1/MIP3 Protein [NBP2-35021]

SDS-Page: Human CCL23/Ck beta 8-1/MIP3 Protein [NBP2-35021]

Formulation, Preparation and Storage

NBP2-35021
Formulation Lyophilized from a 0.2 um filtered concentrated solution in 20 mM PB, pH 7.4, 150 mM NaCl.
Preservative No Preservative
Concentration Lyoph
Reconstitution Recommended to centrifuge prior to opening. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/mL. Apportion stock solutions into working aliquots and store at <-20C.
Format Carrier-Free
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at -20 to -70C as supplied. After reconstitution, store at 2 to 8C for 1 month and at -20 to -70C for long term storage. Avoid repeated freeze-thaw cycles.

Background: CCL23/Ck beta 8-1

CCL23 is a member of CC chemokine family and is encoded by CCL23 gene located on Chr.17 in humans, where near several other CC chemokines. Highly expressed in adult lung, liver, skeletal muscle and pancreas, this protein shows strong chemotactic activity for monocytes, resting T-lymphocytes, and neutrophils, but not for activated lymphocytes. It elicits the effects by binding to CCR1. CCL23 is reported that it can be cleaved into four forms: CCL23 (19-99), CCL23 (22-99), CCL23 (27-99), CCL23 (30- 99).

Alternate Names

Ck beta 8-1, Ckb81, MIP-3, MIP-3/CCL23

Gene Symbol

CCL23

UniProt

Additional CCL23/Ck beta 8-1 Products

Product Documents for Recombinant Human CCL23/Ck beta 8-1/MIP3 Protein

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Recombinant Human CCL23/Ck beta 8-1/MIP3 Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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