Recombinant Human CCS/SOD4 His Protein

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-48393

Novus Biologicals, part of Bio-Techne
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NBP1-48393-0.5mg
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Key Product Details

Source

E. coli

Tag

His

Conjugate

Unconjugated

Applications

SDS-PAGE

View all CCS/SOD4 Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-274 of Human CCS/SOD4

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MASDSGNQGT LCTLEFAVQM TCQSCVDAVR KSLQGVAGVQ DVEVHLEDQM VLVHTTLPSQ EVQALLEGTG RQAVLKGMGS GQLQNLGAAV AILGGPGTVQ GVVRFLQLTP ERCLIEGTID GLEPGLHGLH VHQYGDLTNN CNSCGNHFNP DGASHGGPQD SDRHRGDLGN VRADADGRAI FRMEDEQLKV WDVIGRSLII DEGEDDLGRG GHPLSKITGN SGERLACGII ARSAGLFQNP KQICSCDGLT IWEERGRPIA GKGRKESAQP PAHL

Purity

>90%, by SDS-PAGE

Predicted Molecular Mass

31.2 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human CCS/SOD4 His Protein

SDS-PAGE: Recombinant Human CCS/SOD4 His Protein [NBP1-48393]

SDS-PAGE: Recombinant Human CCS/SOD4 His Protein [NBP1-48393]

SDS-Page: Recombinant Human CCS/SOD4 Protein [NBP1-48393] - 15 % SDS-PAGE (3ug)

Formulation, Preparation and Storage

NBP1-48393
Formulation 20 mM Tris-HCl buffer (pH8.0), 0.2 M NaCl, 1 mM DTT, 10% glycerol
Preservative No Preservative
Concentration 1 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CCS/SOD4

CCS is essential for the incorporation of copper into SOD-1, and therefore is necessary for its enzymatic activity. CCS prevents copper ions from binding to intracellular copper scavengers and provides the SOD-1 enzyme with the necessary copper cofactor. CCS escorts copper only to SOD-1 and fails to deliver copper to proteins in the mitochondria, nucleus or secretory pathway. While many tissues express CCS, the chaperone is most abundant in the kidney, liver and Purkinje cells in the neuropil of the central nervous system. Recombinant human CCS protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Alternate Names

copper chaperone for superoxide dismutase, MGC138260, Superoxide dismutase copper chaperone

Gene Symbol

CCS

Additional CCS/SOD4 Products

Product Documents for Recombinant Human CCS/SOD4 His Protein

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Recombinant Human CCS/SOD4 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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