Recombinant Human CLPS His Protein

Name: Recombinant Human CLPS His Protein
Brand: Novus Biologicals
SKU: NBP2-51686

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-51686

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Technical Data
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Product Specifications
Scientific Data
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Source

E. coli

Tag

His

Conjugate

Unconjugated

Applications

SDS-PAGE

View all CLPS Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 18-112 of Human CLPS

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSAPGPRGI IINLENGELC MNSAQCKSNC CQHSSALGLA RCTSMASENS ECSVKTLYGI YYKCPCERGL TCEGDKTIVG SITNTNFGIC HDAGRSKQ

Purity

>90%, by SDS-PAGE

Predicted Molecular Mass

12.5 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human CLPS His Protein

SDS-PAGE: Recombinant Human CLPS His Protein [NBP2-51686]

SDS-Page: CLPS Recombinant Protein [NBP2-51686] - 15% SDS Page (3 ug)

Formulation, Preparation and Storage

NBP2-51686

Formulation	20 mM Tris-HCl buffer (pH8.0), 30% glycerol, 1 mM DTT, 0.1 M NaCl
Preservative	No Preservative
Concentration	0.25 mg/ml
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CLPS

The protein encoded by the CLPS gene is a cofactor needed by pancreatic lipase for efficient dietary lipid hydrolysis. It binds to the C-terminal, non-catalytic domain of lipase, thereby stabilizing an active conformation and considerably increasing the overall hydrophobic binding site. The gene product allows lipase to anchor noncovalently to the surface of lipid micelles, counteracting the destabilizing influence of intestinal bile salts. This cofactor is only expressed in pancreatic acinar cells, suggesting regulation of expression by tissue-specific elements.

Alternate Names

colipase, colipase, pancreatic, pancreatic colipase preproprotein

Gene Symbol

CLPS

Additional CLPS Products

Product Documents for Recombinant Human CLPS His Protein

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COA

Product Specific Notices for Recombinant Human CLPS His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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