Recombinant Mouse Cochlin FLAG Protein

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-18160

Novus Biologicals, part of Bio-Techne
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NBP3-18160
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Key Product Details

Source

HEK293

Accession #

Q62507

Tag

FLAG

Conjugate

Unconjugated

Applications

SDS-PAGE

View all Cochlin Proteins and Enzymes »

Product Specifications

Description

Mouse cochlin (LCCL domain) (aa 27-134) fused at the N-terminus to a FLAG(R)-tag.

Source: HEK 293 cells Uniprot ID: Q62507

TMW: ~8kDa and 18kDa

Purity

>95% pure by SDS-PAGE

Endotoxin Level

<0.01EU/ug purified protein (LAL test; Lonza).

Protein / Peptide Type

Recombinant Protein

Formulation, Preparation and Storage

NBP3-18160
Formulation Lyophilized from PBS
Preservative No Preservative
Concentration Lyoph
Reconstitution Reconstitute with 100 ul sterile water (0.1mg/ml after reconstitution)
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Cochlin

COCH is encoded by this gene is highly conserved in human, mouse, and chicken, showing 94% and 79% amino acid identity of human to mouse and chicken sequences, respectively. Hybridization to this gene was detected in spindle-shaped cells located along nerve fibers between the auditory ganglion and sensory epithelium. These cells accompany neurites at the habenula perforata, the opening through which neurites extend to innervate hair cells. This and the pattern of expression of this gene in chicken inner ear paralleled the histologic findings of acidophilic deposits, consistent with mucopolysaccharide ground substance, in temporal bones from DFNA9 (autosomal dominant nonsyndromic sensorineural deafness 9) patients. Mutations that cause DFNA9 have been reported in this gene. Alternative splicing results in multiple transcript variants encoding the same protein. Additional splice variants encoding distinct isoforms have been described but their biological validities have not been demonstrated. [provided by RefSeq]

Alternate Names

COCH, COCH5B2, DFNA31, DFNA9

Gene Symbol

COCH

UniProt

Q62507 (Mouse)

Additional Cochlin Products

Product Documents for Recombinant Mouse Cochlin FLAG Protein

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Recombinant Mouse Cochlin FLAG Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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