COMT Antibody Blocking Peptide

Name: COMT Antibody Blocking Peptide
Brand: Novus Biologicals
SKU: NB100-1780PEP

Novus Biologicals, part of Bio-Techne | Catalog # NB100-1780PEP

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Product Datasheet / COA

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Product Specifications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Source

Synthetic

Conjugate

Unconjugated

Applications

Antibody Competition

View all COMT Proteins and Enzymes »

Product Specifications

Description

A human COMT antibody blocking peptide.

Source: Synthetic

Amino Acid Sequence: GDTKEQRILNHVLQC

Purity

>50%, by HPLC

Application Notes

This peptide is useful as a blocking peptide for NB100-1780. For further blocking peptide related protocol, click here.

Protein / Peptide Type

Antibody Blocking Peptide

Formulation, Preparation and Storage

NB100-1780PEP

Formulation	Lyophilized from a 5pmol/ul solution in 5% (v/v) acetonitrile/H2O and TFA salt.
Preservative	No Preservative
Concentration	Lyoph
Reconstitution	Reconstitute in 200ul distilled water to obtain a 0.5mg/ml peptide solution.
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at -20C. Avoid freeze-thaw cycles.

Background: COMT

Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. The transcript variants are formed through the use of alternative translation initiation sites and promoters.

Long Name

Catechol O-Methyltransferase

Alternate Names

catechol O-methyltransferase, catechol-O-methyltransferase, EC 2.1.1.6

Gene Symbol

COMT

Additional COMT Products

Product Documents for COMT Antibody Blocking Peptide

Product Datasheets

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COA

Product Specific Notices for COMT Antibody Blocking Peptide

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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