Recombinant Rat CXCL7/NAP-2 Protein

Name: Recombinant Rat CXCL7/NAP-2 Protein
Brand: Novus Biologicals
SKU: NBP2-35279

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-35279

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Product Specifications
Scientific Data
Preparation & Storage
Background
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Specific Notices

Key Product Details

Source

E. coli

Conjugate

Unconjugated

Applications

Bioactivity, SDS-PAGE

View all CXCL7/NAP-2 Proteins and Enzymes »

Product Specifications

Description

A single non-glycosylated polypeptide chain containing 62 amino acids corresponding to CXCL7/NAP-2 Source: E. coli

Amino Acid Sequence: IELRCRCTNT LSGIPLNSIS RVNVFRPGAH CDNVEVIATL KNGKEVCLDP TAPMIKKIVK KI

Purity

> 97 % pure by SDS-PAGE and HPLC

Endotoxin Level

Less than 1 EU/ug of CXCL7/NAP-2 as determined by LAL method.

Predicted Molecular Mass

6.8 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Activity

NAP2 Protein is fully biologically active when compared to standard. The biologically active determined by a chemotaxis bioassay using human CXCR2 transfected murine BaF3 cells is in a concentration range of 0.1-1.0 ng/ml.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Rat CXCL7/NAP-2 Protein

SDS-PAGE: Recombinant Rat CXCL7/NAP-2 Protein [NBP2-35279]

SDS-Page: Rat CXCL7/NAP-2 Protein [NBP2-35279]

Formulation, Preparation and Storage

NBP2-35279

Formulation	Lyophilized from a 0.2 um filtered concentrated solution in PBS, pH 7.4.
Preservative	No Preservative
Concentration	Lyoph
Reconstitution	Recommended to centrifuge prior to opening. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/mL.
Format	Carrier-Free
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at -20 to -70C as supplied. After reconstitution, store at 2 to 8C for 1 month and at -20 to -70C for long term storage. Avoid repeated freeze-thaw cycles.

Background: CXCL7/NAP-2

CXCL7 is a small cytokine which is also an isoform of Beta-Thromboglobulin or Pro-Platelet basic protein belonging to the CXC chemokine family and it is released in large amounts from platelets following their activation. CXCL7 stimulates DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by human synovial cells. Recombinant Rat CXCL7 contains 62 amino acids which is a single non-glycosylated polypeptide chain. In addition, The rat CXCL7 shares 58 % and 77 % a.a. sequence identity with human and mouse CXCL7.

Alternate Names

CTAP III, NAP-2, NAP2, PPBP, CXCL7, NAP-2/CXCL7

Gene Symbol

PPBP

Additional CXCL7/NAP-2 Products

Product Documents for Recombinant Rat CXCL7/NAP-2 Protein

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COA

Product Specific Notices for Recombinant Rat CXCL7/NAP-2 Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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