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Recombinant Human DUSP18 His Protein

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-99084

Novus Biologicals, part of Bio-Techne
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NBP1-99084-0.5mg
NBP1-99084-100ug

Key Product Details

Source

E. coli

Tag

His

Conjugate

Unconjugated

Applications

SDS-PAGE

Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-188 of Human DUSP18

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMTAPSC AFPVQFRQPS VSGLSQITKS LYISNGVAAN NKLMLSSNQI TMVINVSVEV VNTLYEDIQY MQVPVADSPN SRLCDFFDPI ADHIHSVEMK QGRTLLHCAA GVSRSAALCL AYLMKYHAMS LLDAHTWTKS CRPIIRPNSG FWEQLIHYEF QLFGKNTVHM VSSPVGMIPD IYEKEVRLMI PL

Purity

>95%, by SDS-PAGE

Predicted Molecular Mass

23.6 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human DUSP18 His Protein

SDS-PAGE: Recombinant Human DUSP18 His Protein [NBP1-99084]

SDS-PAGE: Recombinant Human DUSP18 His Protein [NBP1-99084]

SDS-Page: Recombinant Human DUSP18 Protein [NBP1-99084] - 3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain

Formulation, Preparation and Storage

NBP1-99084
Formulation 20 mM Tris-HCl buffer (pH 8.0), 1 mM DTT, 40% glycerol, 0.1 mM PMSF, 1 mM EDTA
Preservative No Preservative
Concentration 0.5 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: DUSP18

Dual specificity phosphatase 18, also known as DUSP18, is a member of the dual-specificity phosphatase (DSP) family, which catalyzes dephosphorylation of phosphotyrosine and phosphothreonine residues. DUSP18 is inhibited by iodoarectic acid and is activated by manganese ions. Along with having preferential enzymatic activity against phosphorylated tyrosine residues over threonine residues, DUSP18 also dephosphorylates p-nitrophenyl phosphate (pNPP) in vitro. This protein is widely expressed with highest levels in liver, brain, ovary and testis. Recombinant human DUSP18 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Alternate Names

bK963H5.1, DSP18, dual specificity phosphatase 18, dual specificity protein phosphatase 18, DUSP20, EC 3.1.3.16, EC 3.1.3.48, LMWDSP20, LMW-DSP20, Low molecular weight dual specificity phosphatase 20, MGC32658

Gene Symbol

DUSP18

Additional DUSP18 Products

Product Documents for Recombinant Human DUSP18 His Protein

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Recombinant Human DUSP18 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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