Recombinant Human Endothelin-3 His Protein

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-51961

Novus Biologicals, part of Bio-Techne
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NBP2-51961-0.05mg
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Key Product Details

Source

E. coli

Tag

His

Conjugate

Unconjugated

Applications

SDS-PAGE

View all Endothelin-3 Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 26-238 of Human Endothelin-3

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSGDAGRRG VSQAPTAARS EGDCEETVAG PGEETVAGPG EGTVAPTALQ GPSPGSPGQE QAAEGAPEHH RSRRCTCFTY KDKECVYYCH LDIIWINTPE QTVPYGLSNY RGSFRGKRSA GPLPGNLQLS HRPHLRCACV GRYDKACLHF CTQTLDVSSN SRTAEKTDKE EEGKVEVKDQ QSKQALDLHH PKLMPGSGLA LAPSTCPRCL FQEGAP

Purity

>85%, by SDS-PAGE

Predicted Molecular Mass

25.2 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human Endothelin-3 His Protein

SDS-PAGE: Recombinant Human Endothelin-3 His Protein [NBP2-51961]

SDS-PAGE: Recombinant Human Endothelin-3 His Protein [NBP2-51961]

SDS-Page: Recombinant Human Endothelin-3 Protein [NBP2-51961] - 15% SDS Page (3 ug)

Formulation, Preparation and Storage

NBP2-51961
Formulation PBS (pH 7.4), 10% glycerol
Preservative No Preservative
Concentration 0.25 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Endothelin-3

Endothelin 3 is encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Four alternatively spliced transcript variants encoding three distinct isoforms have been observed. [provided by RefSeq]

Alternate Names

EDN3, Endothelin3

Gene Symbol

EDN3

Additional Endothelin-3 Products

Product Documents for Recombinant Human Endothelin-3 His Protein

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Recombinant Human Endothelin-3 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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