Recombinant Human GAP-43 His Protein
Novus Biologicals, part of Bio-Techne | Catalog # NBP2-53033
Key Product Details
Source
E. coli
Tag
His
Conjugate
Unconjugated
Applications
SDS-PAGE
Product Specifications
Description
A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-238 of Human GAP-43
Source: E.coli
Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMLCCMR RTKQVEKNDD DQKIEQDGIK PEDKAHKAAT KIQASFRGHI TRKKLKGEKK DDVQAAEAEA NKKDEAPVAD GVEKKGEGTT TAEAAPATGS KPDEPGKAGE TPSEEKKGEG DAATEQAAPQ APASSEEKAG SAETESATKA STDNSPSSKA EDAPAKEEPK QADVPAAVTA AAATTPAAED AAAKATAQPP TETGESSQAE ENIEAVDETK PKESARQDEG KEEEPEADQE HA
Purity
>90%, by SDS-PAGE
Predicted Molecular Mass
27.3 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Protein / Peptide Type
Recombinant Protein
Scientific Data Images for Recombinant Human GAP-43 His Protein
![SDS-PAGE: Recombinant Human GAP-43 His Protein [NBP2-53033]](https://resources.bio-techne.com/images/products/GAP-43-Recombinant-Protein-SDS-Page-NBP2-53033-img0001.jpg "SDS-PAGE: Recombinant Human GAP-43 His Protein [NBP2-53033]")
SDS-PAGE: Recombinant Human GAP-43 His Protein [NBP2-53033]
SDS-Page: Recombinant Human GAP-43 Protein [NBP2-53033] - 15% SDS-PAGE (3ug)Formulation, Preparation and Storage
NBP2-53033
| Formulation | 20 mM Tris-HCl buffer (pH 8.0), 0.1 M NaCl, 10% glycerol |
| Preservative | No Preservative |
| Concentration | 0.5 mg/ml |
| Shipping | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| Stability & Storage | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Background: GAP-43
Heterozygous GAP3 knockout mice with GAP-43 levels reduced by one-half display significant memory impairments in cued conditioning, or on tests of nociceptive or auditory perception. Differentiating neurons that do not express GAP-43 show mislocalization of the centrosome and mitotic spindles, particularly in neurogenic cell divisions. Therefore, the neuronal precursor pool in the cerebellum fails to grow resulting in a cerebellum that is significantly smaller than normal. Total GAP-43 deletion is lethal within days of birth, demonstrating that GAP-43 is critical for the proper development of the mammalian CNS.
Long Name
Growth Associated Protein 43
Alternate Names
B-50, Basp2, GAP43, Neuromodulin
Gene Symbol
GAP43
Additional GAP-43 Products
Product Documents for Recombinant Human GAP-43 His Protein
Product Specific Notices for Recombinant Human GAP-43 His Protein
This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.
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