Amino Acid Sequence: MCAAQMPPLA HIFRGTFVHS TWTCPMEVLR DHLLGVSDSG KIVFLEEASQ QEKLAKEWCF KPCEIRELSH HEFFMPGLVD THIHASQYSF AGSSIDLPLL EWLTKYTFPA EHRFQNIDFA EEVYTRVVRR TLKNGTTTAC YFATIHTDSS LLLADITDKF GQRAFVGKVC MDLNDTFPEY KETTEESIKE TERFVSEMLQ KNYSRVKPIV TPRFSLSCSE TLMGELGNIA KTRDLHIQSH ISENRDEVEA VKNLYPSYKN YTSVYDKNNL LTNKTVMAHG CYLSAEELNV FHERGASIAH CPNSNLSLSS GFLNVLEVLK HEVKIGLGTD VAGGYSYSML DAIRRAVMVS NILLINKVNE KSLTLKEVFR LATLGGSQAL GLDGEIGNFE VGKEFDAILI NPKASDSPID LFYGDFFGDI SEAVIQKFLY LGDDRNIEEV YVGGKQVVPF SSSV

Purity

>90%, by SDS-PAGE

Predicted Molecular Mass

51 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Activity

Specific activity is > 2,000 pmol/min/ug, and is defined as the amount of enzyme that convert guanine to xanthine per minute at pH 8.0 at 37C.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human Guanine deaminase Protein

Recombinant Human Guanine deaminase Protein [NBP2-49692]

Formulation, Preparation and Storage

NBP2-49692

Formulation	PBS (pH 7.4), 10% glycerol, 1 mM DTT
Preservative	No Preservative
Concentration	1 mg/ml
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Guanine deaminase

GDA, also known as guanine deaminase isoform b, catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia. Studies in rat ortholog suggest this gene plays a role in microtubule assembly. Multiple transcript variants encoding different isoforms have been found for this gene. Recombinant human GDA, was expressed in E.coli and purified by conventional chromatography techniques. Produced in E. coli

Alternate Names

CYPIN, EC 3.5.4.3, GAH, Guanase, Guanine aminase, Guanine aminohydrolase, guanine deaminase, KIAA1258, MGC9982, NEDASIN, p51-nedasin

Gene Symbol

GDA

Additional Guanine deaminase Products

Product Documents for Recombinant Human Guanine deaminase Protein

Product Datasheets

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COA

Product Specific Notices for Recombinant Human Guanine deaminase Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

Citations
Reviews

Recombinant Human Guanine deaminase Protein

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-49692

Key Product Details

Source

Conjugate

Applications

View all Guanine deaminase Proteins and Enzymes »

Product Specifications

Description