HAAO Antibody Blocking Peptide

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-77361PEP

Novus Biologicals, part of Bio-Techne
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NBP1-77361PEP
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Key Product Details

Source

Synthetic

Conjugate

Unconjugated

Applications

Antibody Competition

View all HAAO Proteins and Enzymes »

Product Specifications

Description

A blocking peptide containing 17 amino acids near the amino terminus of human HAAO.

Source: Synthetic

(Accession #: NP_036337)

Purity

N/A

Application Notes

This peptide is useful as a blocking peptide for NBP1-77361.

For further blocking peptide related protocol, click here.

Protein / Peptide Type

Antibody Blocking Peptide

Formulation, Preparation and Storage

NBP1-77361PEP
Formulation PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin.
Preservative 0.02% Sodium Azide
Concentration 0.2 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at -20C. Avoid freeze-thaw cycles.

Background: HAAO

3-Hydroxyanthranilate 3,4-dioxygenase is a monomeric cytosolic protein belonging to the family of intramolecular dioxygenases containing nonheme ferrous iron. It is widely distributed in peripheral organs, such as liver and kidney, and is also present in low amounts in the central nervous system. HAAO catalyzes the synthesis of quinolinic acid (QUIN) from 3-hydroxyanthranilic acid. QUIN is an excitotoxin whose toxicity is mediated by its ability to activate glutamate N-methyl-D-aspartate receptors. Increased cerebral levels of QUIN may participate in the pathogenesis of neurologic and inflammatory disorders. HAAO has been suggested to play a role in disorders associated with altered tissue levels of QUIN. [provided by RefSeq]

Alternate Names

3-HAO, 3-hydroxyanthranilate 3,4-dioxygenase, 3-hydroxyanthranilic acid dioxygenase, EC 1.13.11.6,3-hydroxyanthranilate oxygenase, HAD, HAO

Gene Symbol

HAAO

Additional HAAO Products

Product Documents for HAAO Antibody Blocking Peptide

Product Datasheets

Certificate of Analysis

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Product Specific Notices for HAAO Antibody Blocking Peptide

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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