Recombinant Rat HO-1/HMOX1/HSP32 His Protein

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-18328

Novus Biologicals, part of Bio-Techne
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Key Product Details

Tag

His

Conjugate

Unconjugated

Applications

SDS-PAGE, Western Blot

View all HO-1/HMOX1/HSP32 Proteins and Enzymes »

Product Specifications

Description

A partial recombinant protein corresponding to rat HO-1/HMOX1/HSP32.

Source: E. coli

Amino Acid Sequence: MERPQLDSMSQDLSEALKEATKEVHIRAENSEFMRNFQKGQVSREGFKLVMASLYHIYTALEEEIERNKQNPVYAPLYFPEELHRRAALEQDMAFWYGPHWQEAIPYTPATQHYVKRLHEVGGTHPELLVAHAYTRYLGDLSGGQVLKKIAQKAMALPSSGEGLAFFTFPSIDNPTKFKQLYRARMNTLEMTPEVKHRVTEEAKTAFLLNIELFEELQALLTEEHKDQSPSQTEFLRQRPASLVQDTTSAETPRGKSQIST

Purity

>85%

Predicted Molecular Mass

32 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Localization

Microsome|Endoplasmic Reticulum

Protein / Peptide Type

Partial Recombinant Protein

Scientific Data Images for Recombinant Rat HO-1/HMOX1/HSP32 His Protein

SDS-PAGE: Recombinant Rat HO-1/HMOX1/HSP32 His Protein [NBP3-18328]

SDS-PAGE: Recombinant Rat HO-1/HMOX1/HSP32 His Protein [NBP3-18328]

SDS-Page: Recombinant Rat HO-1/HMOX1/HSP32 His Protein [NBP3-18328] - SDS-PAGE of ~32 kDa rat HO-1/HMOX1/HSP32 protein (NBP3-18328).

Formulation, Preparation and Storage

NBP3-18328
Preparation Method This protein is affinity purified.
Formulation 50mM Tris/HCl pH7.5, 5mM Bme, 0.15NaCl, 10% glycerol
Preservative No Preservative
Concentration Please see the vial label for concentration. If unlisted please contact technical services.
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at -20C. Avoid freeze-thaw cycles.

Background: HO-1/HMOX1/HSP32

Stressed mammalian cells up-regulate heme oxygenase 1 (HO-1), which catabolizes heme to biliverdin, carbon monoxide, and free iron. Results provide genetic evidence that up-regulation of HO-1 serves as an adaptive mechanism to protect cells from oxidative damage during stress (1). When cells are injured they release their contents, resulting in a local accumulation of free heme proteins and heme. HO-1 plays a crucial role in the inflammatory process during wound healing (2). TNFalpha accelerates inflammatory responses by down-regulating HO-1 expression in human monocytes. TNF antagonists may block this TNF-dependent suppression of HO-1 expression, resulting in an amelioration of inflammation (3).

Long Name

Heme Oxygenase 1

Alternate Names

HMOX1, HO1, HSP32

Gene Symbol

HMOX1

Additional HO-1/HMOX1/HSP32 Products

Product Documents for Recombinant Rat HO-1/HMOX1/HSP32 His Protein

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Recombinant Rat HO-1/HMOX1/HSP32 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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