Recombinant Human HSPC132 His Protein

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-22873

Novus Biologicals, part of Bio-Techne
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Key Product Details

Source

E. coli

Tag

His

Conjugate

Unconjugated

Applications

SDS-PAGE

View all HSPC132 Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-76 of Human HSPC132

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSMNSVGEA CTDMKREYDQ CFNRWFAEKF LKGDSSGDPC TDLFKRYQQC VQKAIKEKEI PIEGLEFMGH GKEKPENSS

Purity

>90%, by SDS-PAGE

Predicted Molecular Mass

11.2 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human HSPC132 His Protein

SDS-PAGE: Recombinant Human HSPC132 His Protein [NBP2-22873]

SDS-PAGE: Recombinant Human HSPC132 His Protein [NBP2-22873]

SDS-Page: Recombinant Human HSPC132 Protein [NBP2-22873]

Formulation, Preparation and Storage

NBP2-22873
Formulation 20 mM Tris-HCl buffer (pH 8.0), 0.1 M NaCl, 20% glycerol, 1 mM DTT
Preservative No Preservative
Concentration 1 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: HSPC132

TP53-regulated inhibitor of apoptosis 1, also known as TRIAP1, contains a p53-binding site within its second exon and the reduction of expression by small interfering RNA enhanced apoptosis, whereas overexpression protected cells from apoptosis caused by DNA damage. TRIAP1 is induced significantly when cells have a low level of genotoxic stresses, but not when DNA damage is severe. TRIAP1 can modulate apoptotic pathways through interaction with Hsp70 that probably inhibits activity of apoptosis protease activating factor-1. Recombinant human TRIAP1, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Alternate Names

15E1.1, MDM35, MDM-35, Mitochondrial Distribution And Morphology 35 Homolog, P53CSV, P53-Inducible Cell-Survival Factor, Protein 15E1.1, TP53 regulated inhibitor of apoptosis 1, TP53-Regulated Inhibitor Of Apoptosis, TRIAP1, WF-1

Gene Symbol

TRIAP1

Additional HSPC132 Products

Product Documents for Recombinant Human HSPC132 His Protein

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Recombinant Human HSPC132 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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