Recombinant Human ICEBERG His Protein

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-98862

Novus Biologicals, part of Bio-Techne
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NBP1-98862-50ug
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Key Product Details

Source

E. coli

Tag

His

Conjugate

Unconjugated

Applications

SDS-PAGE

View all ICEBERG Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-90 of Human ICEBERG

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MADQLLRKKR RIFIHSVGAG TINALLDCLL EDEVISQEDM NKVRDENDTV MDKARVLIDL VTGKGPKSCC KFIKHLCEED PQLASKMGLH

Purity

>95%, by SDS-PAGE

Predicted Molecular Mass

12.3 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human ICEBERG His Protein

SDS-PAGE: Recombinant Human ICEBERG His Protein [NBP1-98862]

SDS-PAGE: Recombinant Human ICEBERG His Protein [NBP1-98862]

SDS-Page: Recombinant Human ICEBERG Protein [NBP1-98862] - 15% SDS-PAGE (3ug)

Formulation, Preparation and Storage

NBP1-98862
Formulation 20 mM Tris-HCl buffer (pH 8.0), 1 mM DTT,10% glycerol, 0.1 M NaCl
Preservative No Preservative
Concentration 0.5 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ICEBERG

Caspase recruitment domain-containing protein 18, also known as CARD18, is a member of the death-domain-fold superfamily that is induced by proinflammatory stimuli. It consists essentially only of a CARD, inhibits generation of IL-1b by interacting with caspase-1 and preventing association with RIP 2. The association of CARD18 with caspase-1 is facilitated by the charge-charge interactions between the prodomain of caspase-1 and the surface charge of CARD18. Recombinant human CARD18 proetin, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Alternate Names

caspase recruitment domain family, member 18, Caspase-1 inhibitor Iceberg, ICEBERG caspase-1 inhibitor, ICEBERGcaspase recruitment domain-containing protein 18, pseudo-ICE, UNQ5804

Gene Symbol

CARD18

Additional ICEBERG Products

Product Documents for Recombinant Human ICEBERG His Protein

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Recombinant Human ICEBERG His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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