Recombinant Human IGFL-3 FLAG Protein

Name: Recombinant Human IGFL-3 FLAG Protein
Brand: Novus Biologicals
SKU: NBP3-18152

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-18152

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Product Datasheet / COA

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Product Specifications
Scientific Data
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Source

HEK293

Accession #

Q6UXB1

Tag

FLAG

Conjugate

Unconjugated

Applications

Bioactivity, ELISA

View all IGFL-3 Proteins and Enzymes »

Product Specifications

Description

Human IGFL-3 (aa 25-125) fused at the N-terminus to a FLAG(R)-tag.

Source: HEK 293 cells

Uniprot ID: Q6UXB1

Purity

>95% pure by SDS-PAGE

Endotoxin Level

<0.5EU/ug purified protein (LAL test; Lonza).

Predicted Molecular Mass

12 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Activity

Binds to human IGFLR1

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human IGFL-3 FLAG Protein

ELISA: Recombinant Human IGFL-3 FLAG Protein [NBP3-18152]

ELISA: Recombinant Human IGFL-3 FLAG Protein [NBP3-18152] - IGFL3 (human) binds to its receptor IGFLR1 (human):Fc (human) or a negative control, Omentin (human) during one hour and then detected using an anti-FLAG(R) antibody (HRP).

Formulation, Preparation and Storage

NBP3-18152

Formulation	Lyophilized from PBS
Preservative	No Preservative
Concentration	Lyoph
Reconstitution	Reconstitute with 100 ul sterile water (0.1mg/ml after reconstitution)
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: IGFL-3

Insulin-like growth factor (IGF)-I (also known as somatomedin C and somatomedin A) and IGF-II (multiplication stimulating activity or MSA) belong to the family of insulin-like growth factors that are structurally homologous to proinsulin. Mature IGF-I and IGF-II share approximately 70% sequence identity. Both IGF-I and IGF-II are expressed in many tissues and cell types and may have autocrine, paracrine and endocrine functions. Mature IGF-I and IGF-II are highly conserved between the human, bovine and porcine proteins (100% identity), and exhibit cross-species activity.

The IGFL (insulin-like growth factor-like) family includes four small (~11 kDa), probably secreted family members in humans and one in mouse. This family shares A and B chain cysteine motifs with the IGF superfamily, and has an additional cysteine motif within an uncleaved region corresponding to the C peptide of the IGF family.

Long Name

IGF-like Family Member 3

Alternate Names

IGFL3

Gene Symbol