Recombinant Guinea Pig IL-17/IL-17A Protein

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-11059

Novus Biologicals, part of Bio-Techne
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NBP3-11059
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Key Product Details

Accession #

A0A286XFR9

Conjugate

Unconjugated

Applications

ELISA, Western Blot

View all IL-17/IL-17A Proteins and Enzymes »

Product Specifications

Description

Recombinant Guinea Pig Interleukin-17A (IL-17A) is a recombinant protein corresponding to aa 25-158 of native guinea pig IL-17A.

Purity

>95%, by SDS-PAGE

Predicted Molecular Mass

17 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Guinea Pig IL-17/IL-17A Protein

ELISA: Recombinant Guinea Pig IL-17/IL-17A Protein [NBP3-11059]

ELISA: Recombinant Guinea Pig IL-17/IL-17A Protein [NBP3-11059]

ELISA: Recombinant Guinea Pig IL-17/IL-17A Protein [NBP3-11059] - Recombinant Guinea Pig Inetrleukin-17A (NBP3-11059) detected using Rabbit anti Guinea Pig Inetrleukin-17A (NBP3-11319) as the capture reagent and Rabbit anti Guinea Pig Inetrleukin-17A:Biotin as the detection reagent followed by Streptavidin:HRP.

Formulation, Preparation and Storage

NBP3-11059
Preparation Method Recombinant protein expressed in Pichia pastoris and purified by ion-exchange chromatography
Formulation PBS
Preservative 10% Trehalose
Concentration Lyoph
Reconstitution Reconstitute with 20 uL sterile PBS containing 0.1% carrier protein. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. We recommend that the vial is gently mixed after reconstitution.
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at -20C. Avoid freeze-thaw cycles.

Background: IL-17/IL-17A

Interleukin 17 (IL-17) is a pro-inflammatory cytokine produced by TCRalpha/beta+ CD4 CD8 thymocytes, as well as by activated CD4+ and CD4+ CD45RO+ memory T cells (1). IL-17 stimulates the expression of TNFalpha, IL-1 beta, IL-6, and IL-8 (2). In addition, IL-17 is involved in the induction of inducible nitric oxide synthase and cyclooxygenase 2 in chondrocytes (3). High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis (4).

Long Name

Interleukin 17

Alternate Names

CTLA-8, CTLA8, IL-17A, IL17, IL17A

Gene Symbol

IL17A

UniProt

A0A286XFR9 (Guinea Pig)

Additional IL-17/IL-17A Products

Product Documents for Recombinant Guinea Pig IL-17/IL-17A Protein

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Recombinant Guinea Pig IL-17/IL-17A Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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