Recombinant Sheep IL-22 Protein

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-11060

Novus Biologicals, part of Bio-Techne
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NBP3-11060
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Key Product Details

Accession #

H2AKX1

Conjugate

Unconjugated

Applications

ELISA, Western Blot

View all IL-22 Proteins and Enzymes »

Product Specifications

Description

Recombinant Sheep Interleukin-22 (IL-22) is a recombinant protein corresponding to aa 34-190 of native sheep IL-22.

Purity

>95%, by SDS-PAGE

Predicted Molecular Mass

18.3 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Sheep IL-22 Protein

ELISA: Recombinant Sheep IL-22 Protein [NBP3-11060]

ELISA: Recombinant Sheep IL-22 Protein [NBP3-11060]

ELISA: Recombinant Sheep IL-22 Protein [NBP3-11060] - Recombinant Sheep Interleukin-22 detected using Rabbit anti Sheep Interleukin-22 as the capture reagent and Rabbit anti Sheep Interleukin-22:Biotin as the detection reagent followed by Streptavidin:HRP.

Formulation, Preparation and Storage

NBP3-11060
Preparation Method Recombinant protein expressed in Pichia pastoris and purified by ion-exchange chromatography.
Formulation PBS
Preservative 10% Trehalose
Concentration Lyoph
Reconstitution Reconstitute with 20 uL sterile PBS containing 0.1% carrier protein. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. We recommend that the vial is gently mixed after reconstitution.
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at -20C. Avoid freeze-thaw cycles.

Background: IL-22

Interleukin-22 (IL-22 or IL-TIF (IL-10-related T-cell derived inducible factor)) belongs to the IL-10 family of regulatory cytokines which also includes IL-10, IL-19, IL-20, IL-24 and IL-26. IL-22 is produced by T lymphocytes following anti-CD3 stimulation. It inhibits IL-4 production of Th2 cells, activates STAT-1 and STAT-3 in several hepatoma cell lines and upregulates the production of acute phase proteins. It may also be involved in inflammatory responses. Human and mouse IL-22 share 79% amino acid identity. Recombinant human IL-22 is a non-disulfide linked homodimer, signaling through a receptor complex of two subunits, IL-22R and IL-10R-beta, belonging to the class II cytokine receptor family.

Long Name

Interleukin 22

Alternate Names

IL-TIF, IL22

Gene Symbol

IL22

UniProt

H2AKX1 (Sheep)

Additional IL-22 Products

Product Documents for Recombinant Sheep IL-22 Protein

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Recombinant Sheep IL-22 Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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