Recombinant Human Lambda5/IGLL1 His Protein

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-23133

Novus Biologicals, part of Bio-Techne
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NBP2-23133
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Key Product Details

Source

E. coli

Tag

His

Conjugate

Unconjugated

Applications

SDS-PAGE

View all Lambda5/IGLL1 Proteins and Enzymes »

Product Specifications

Description

A denatured recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 38-213 of Human Lambda5/IGLL1

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSLLRPTAA SQSRALGPGA PGGSSRSSLR SRWGRFLLQR GSWTGPRCWP RGFQSKHNSV THVFGSGTQL TVLSQPKATP SVTLFPPSSE ELQANKATLV CLMNDFYPGI LTVTWKADGT PITQGVEMTT PSKQSNNKYA ASSYLSLTPE QWRSRRSYSC QVMHEGSTVE KTVAPAECS

Purity

>85%, by SDS-PAGE

Predicted Molecular Mass

21.5 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human Lambda5/IGLL1 His Protein

SDS-PAGE: Recombinant Human Lambda5/IGLL1 His Protein [NBP2-23133]

SDS-PAGE: Recombinant Human Lambda5/IGLL1 His Protein [NBP2-23133]

SDS-Page: IGLL1 Protein [NBP2-23133]

Formulation, Preparation and Storage

NBP2-23133
Formulation 20 mM Tris-HCl buffer (pH 8.0), 0.4M UREA, 10% glycerol
Preservative No Preservative
Concentration 1 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Lambda5/IGLL1

The preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. IGLL1 is one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. This gene does not undergo rearrangement. Mutations in this gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made. Two transcript variants encoding different isoforms have been found for this gene. Recombinant human IGLL1protein, fused to His-tag at N-terminus, was expressed in E.coli.

Long Name

Immunoglobulin Lambda-Like Polypeptide 1

Alternate Names

AGM2, CD179b, IGL5, IGLJ14.1, IGLL1, IGO, IGVPB, VPREB2

Gene Symbol

IGLL1

Additional Lambda5/IGLL1 Products

Product Documents for Recombinant Human Lambda5/IGLL1 His Protein

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Recombinant Human Lambda5/IGLL1 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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