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Recombinant Human MGP His Protein

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-72441

Novus Biologicals, part of Bio-Techne
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NBP1-72441-0.5mg
NBP1-72441-100ug

Key Product Details

Source

E. coli

Tag

His

Conjugate

Unconjugated

Applications

SDS-PAGE

Product Specifications

Description

A denatured recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 20-96 of Human MGP

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MYESHESMES YELNPFINRR NANTFISPQQ RWRAKVQERI RERSKPVHEL NREACDDYRL CERYAMVYGY NAAYNRYF

Purity

>90%, by SDS-PAGE

Predicted Molecular Mass

11.8 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Application Notes

Denatured protein is most likely not the best option for functional studies. It is better suited for Western Blot (WB) or imaging assays.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human MGP His Protein

SDS-PAGE: Recombinant Human MGP His Protein [NBP1-72441]

SDS-PAGE: Recombinant Human MGP His Protein [NBP1-72441]

SDS-Page: Recombinant Human MGP Protein [NBP1-72441]

Formulation, Preparation and Storage

NBP1-72441
Formulation 20 mM Tris-HCl buffer (pH 8.0), 10% glycerol
Preservative No Preservative
Concentration 1 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MGP

MGP, also known as Matrix Gla protein, is a protein involved in regulating calcification in the extracellular matrix, in particular in cartilage and arteries. MGP is a vitamin K-dependent protein, and contains five to six residues of Gla, a Ca2+ binding amino acid requiring vitamin K-dependent gamma carboxylase for its formation. It is found in human bone extracts, likely formed by COOH-terminal processing by carboxypeptidase B-like enzymatic activity. Recombinant human MGP protein, fused to His-tag at N-terminus, was expressed in E.coli and denatured using detergent during a conventional chromatography purification process.

Alternate Names

Cell growth-inhibiting gene 36 protein, matrix Gla protein, MGLAP, NTI

Gene Symbol

MGP

Additional MGP Products

Product Documents for Recombinant Human MGP His Protein

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Recombinant Human MGP His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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