Recombinant Human NKIRAS1 His Protein

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-99105

Novus Biologicals, part of Bio-Techne
Catalog #
Availability
Size / Price
Qty
NBP1-99105-10ug
Print Quote
Bulk Order
100% Guarantee

Key Product Details

Source

E. coli

Tag

His

Conjugate

Unconjugated

Applications

SDS-PAGE

View all NKIRAS1 Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-192 of Human NKIRAS1

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGKGCKVVVC GLLSVGKTAI LEQLLYGNHT IGMEDCETME DVYMASVETD RGVKEQLHLY DTRGLQEGVE LPKHYFSFAD GFVLVYSVNN LESFQRVELL KKEIDKFKDK KEVAIVVLGN KIDLSEQRQV DAEVAQQWAK SEKVRLWEVT VTDRKTLIEP FTLLASKLSQ PQSKSSFPLP GRKNKGNSNS EN

Purity

>85%, by SDS-PAGE

Predicted Molecular Mass

23.8 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human NKIRAS1 His Protein

SDS-PAGE: Recombinant Human NKIRAS1 His Protein [NBP1-99105]

SDS-PAGE: Recombinant Human NKIRAS1 His Protein [NBP1-99105]

SDS-Page: Recombinant Human NKIRAS1 His Protein [NBP1-99105] - 3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain.

Formulation, Preparation and Storage

NBP1-99105
Formulation 20 mM Tris-HCl buffer (pH8.0), 20% glycerol, 1 mM DTT
Preservative No Preservative
Concentration 0.25 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: NKIRAS1

NKIRAS1, also known as NF-kappa-B inhibitor-interacting Ras-like protein 1, belongs to the small GTPase superfamily. NKIRAS1 is atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. It may act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB. Recombinant human NKIRAS1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

Alternate Names

I-kappa-B-interacting Ras-like protein 1, kappa B-ras 1, Kappa B-Ras protein 1, KappaB-Ras1, KBRAS1kappaB-Ras1, NF-kappa-B inhibitor-interacting Ras-like protein 1, NFKB inhibitor interacting Ras-like 1, NFKB inhibitor interacting Ras-like protein 1

Gene Symbol

NKIRAS1

Additional NKIRAS1 Products

Product Documents for Recombinant Human NKIRAS1 His Protein

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Recombinant Human NKIRAS1 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

Privacy and Cookie Policy
Site Map
© Copyright 2024 Bio-Techne. All Rights Reserved.