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Orai1 Antibody Blocking Peptide

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-77289PEP

Novus Biologicals, part of Bio-Techne
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NBP1-77289PEP

Key Product Details

Source

Synthetic

Conjugate

Unconjugated

Applications

Antibody Competition

Product Specifications

Description

A blocking peptide containing 16 amino acids near the carboxy terminus of human ORAI1.

Source: Synthetic

(Accession #: Q96D31)

Purity

N/A

Application Notes

This peptide is useful as a blocking peptide for NBP1-77289.

For further blocking peptide related protocol, click here.

Protein / Peptide Type

Antibody Blocking Peptide

Formulation, Preparation and Storage

NBP1-77289PEP
Formulation PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin.
Preservative 0.02% Sodium Azide
Concentration 0.2 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at -20C. Avoid freeze-thaw cycles.

Background: Orai1

Orai1 is a membrane calcium channel subunit that is activated by the calcium sensor STIM1 when calcium stores are depleted. Orai1 is a pore subunit of Ca(2+) release-activated Ca(2+) CRAC channels, and STIM1 acts as an endoplasmic reticulum (ER) Ca(2+) sensor that detects store depletion. This type of channel is the primary way for calcium influx into T-cells. Defects in Orai1 are a cause of immune dysfunction with T-cell inactivation due to calcium entry defect type 1.

Long Name

ORAI Calcium Release-activated Calcium Modulator 1

Alternate Names

CRACM1, ORAT1, TMEM142A

Gene Symbol

ORAI1

Additional Orai1 Products

Product Documents for Orai1 Antibody Blocking Peptide

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Orai1 Antibody Blocking Peptide

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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