Recombinant Human pan Cadherin His Protein

Name: Recombinant Human pan Cadherin His Protein
Brand: Novus Biologicals
SKU: NBP2-52307

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-52307

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Technical Data
Citations & Reviews

Product Specifications
Scientific Data
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Source

Baculovirus

Tag

His

Conjugate

Unconjugated

Applications

SDS-PAGE

View all Cadherin Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a C-Terminal His-tag and corresponding to the amino acids 24-709 of Human pan Cadherin

Source:Baculovirus

Amino Acid Sequence: QEPEPCHPGF DAESYTFTVP RRHLERGRVL GRVNFEDCTG RQRTAYFSLD TRFKVGTDGV ITVKRPLRFH NPQIHFLVYA WDSTYRKFST KVTLNTVGHH HRPPPHQASV SGIQAELLTF PNSSPGLRRQ KRDWVIPPIS CPENEKGPFP KNLVQIKSNK DKEGKVFYSI TGQGADTPPV GVFIIERETG WLKVTEPLDR ERIATYTLFS HAVSSNGNAV EDPMEILITV TDQNDNKPEF TQEVFKGSVM EGALPGTSVM EVTATDADDD VNTYNAAIAY TILSQDPELP DKNMFTINRN TGVISVVTTG LDRESFPTYT LVVQAADLQG EGLSTTATAV ITVTDTNDNP PIFNPTTYKG QVPENEANVV ITTLKVTDAD APNTPAWEAV YTILNDDGGQ FVVTTNPVNN DGILKTAKGL DFEAKQQYIL HVAVTNVVPF EVSLTTSTAT VTVDVLDVNE APIFVPPEKR VEVSEDFGVG QEITSYTAQE PDTFMEQKIT YRIWRDTANW LEINPDTGAI STRAELDRED FEHVKNSTYT ALIIATDNGS PVATGTGTLL LILSDVNDNA PIPEPRTIFF CERNPKPQVI NIIDADLPPN TSPFTAELTH GASANWTIQY NDPTQESIIL KPKMALEVGD YKINLKLMDN QNKDQVTTLE VSVCDCEGAA GVCRKAQPVE AGLQIPA

Purity

>90%, by SDS-PAGE

Endotoxin Level

< 1.0 EU per 1 microgram of protein (determined by LAL method)

Predicted Molecular Mass

76.8 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human pan Cadherin His Protein

SDS-PAGE: Recombinant Human pan Cadherin His Protein [NBP2-52307]

SDS-Page: Recombinant Human pan Cadherin His Protein [NBP2-52307] - 3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain.

Formulation, Preparation and Storage

NBP2-52307

Formulation	PBS (pH 7.4), 10% glycerol
Preservative	No Preservative
Concentration	0.5 mg/ml
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Cadherin

Cadherins are members of a multigene family of single chain glycoprotein receptors mediating calcium dependent cell-cell adhesion. They play an important role in the growth and development of cells via the mechanisms of control of tissue architecture and the maintenance of tissue integrity. Cadherins are expressed in a tissue specific manner and and are required for assembly of cells into solid tissue. Individual cadherin molecules are known to co-operate with each other to form a linear cell adhesion zipper. In adhesion junctions cadherins are bound to beta and gamma catenins which in turn bind to alpha catenin, an actin binding protein. Cadherins play an important part in tumor invasion and metastasis. This product is useful for the detection of members of the cadherin family or genetically engineered proteins containing the C-terminal cadherin tail, and for demonstration of adherens type cell-cell junctions regardless of their cadherin type.

Long Name

Cadherin Pan Specific

Alternate Names

Arc-1, cadherin 1, E-cadherin (epithelial), cadherin 1, type 1, E-cadherin (epithelial), cadherin-1, calcium-dependent adhesion protein, epithelial, CAM 120/80, CD324, CD324 antigen, CDHE, cell-CAM 120/80, ECAD, E-cadherin, Epithelial cadherin, LCAM, UVOE-Cadherin, Uvomorulin

Gene Symbol

CDH1

Additional Cadherin Products

Product Documents for Recombinant Human pan Cadherin His Protein

Product Datasheets

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COA

Product Specific Notices for Recombinant Human pan Cadherin His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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