Recombinant Mouse Pentraxin 2/SAP His Protein

Name: Recombinant Mouse Pentraxin 2/SAP His Protein
Brand: Novus Biologicals
SKU: NBP2-77502

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-77502

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Product Specifications
Scientific Data
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Source

HEK293

Tag

His

Conjugate

Unconjugated

Applications

SDS-PAGE

View all Pentraxin 2/SAP Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a His-tag and corresponding to the amino acids 21-224 of Mouse Pentraxin2/SAP.

Source: HEK293

Amino Acid Sequence: QTDLKRKVFV FPRESETDHV KLIPHLEKPL QNFTLCFRTY SDLSRSQSLF SYSVKGRDNE LLIYKEKVGE YSLYIGQSKV TVRGMEEYLS PVHLCTTWES SSGIVEFWVN GKPWVKKSLQ REYTVKAPPS IVLGQEQDNY GGGFQRSQSF VGEFSDLYMW DYVLTPQDIL FVYRDSPVNP NILNWQALNY EINGYVVIRP RVWDHHHHHH

Purity

>90%, by SDS-PAGE

Endotoxin Level

< 1.0 EU per 1ug of protein (determined by LAL method)

Predicted Molecular Mass

24.6 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Mouse Pentraxin 2/SAP His Protein

SDS-PAGE: Recombinant Mouse Pentraxin 2/SAP His Protein [NBP2-77502]

SDS-Page: Recombinant Mouse Pentraxin 2/SAP His Protein [NBP2-77502] - 3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain.

Formulation, Preparation and Storage

NBP2-77502

Formulation	PBS (pH 7.4), 10% glycerol.
Preservative	No Preservative
Concentration	0.25 mg/ml
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Pentraxin 2/SAP

Serum Amyloid P (SAP) is a non-fibrillar plasma glycoprotein that belongs to the pentraxin family. It is universally found in amyloid deposits and this is probably due to its specific calcium-dependent binding to motifs present on all types of amyloid fibrils. SAP is also found to prevent fibrillar breakdown by enzymes and it is believed that it helps maintains stability of the amyloid deposits (1,2). It has been shown that SAP binds monocytes with high avidity, but does not bind to erythrocytes, NK cells, T lymphocytes or B lymphocytes (3). SAP production can be induced by exposure to IL-1, IL-6 and IFN-beta. The SAP-inducing activity was neutralized by antibodies to each of the recombinant cytokines (4).

Long Name

Serum Amyloid P Component

Alternate Names

APCS, PTX2, SAP

Gene Symbol

APCS

Additional Pentraxin 2/SAP Products

Product Documents for Recombinant Mouse Pentraxin 2/SAP His Protein

Product Datasheets

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COA

Product Specific Notices for Recombinant Mouse Pentraxin 2/SAP His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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