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Recombinant Human PMP22 GST (N-Term) Protein

Novus Biologicals, part of Bio-Techne | Catalog # H00005376-P01

Novus Biologicals, part of Bio-Techne
Discontinued Product
H00005376-P01 has been discontinued. View all PMP22 products.

Key Product Details

Source

Wheat germ

Tag

GST (N-Term)

Conjugate

Unconjugated

Applications

ELISA, Affinity Purification, Microarray, SDS-PAGE, Western Blot

Product Specifications

Description

Recombinant protein with GST tag at N-terminal corresponding to the amino acids 1-160 of Human PMP22

Source: Wheat Germ (in vitro)

Amino Acid Sequence: MLLLLLSIIVLHVAVLVLLFVSTIVSQWIVGNGHATDLWQNCSTSSSGNVHHCFSSSPNEWLQSVQATMILSIIFSILSLFLFFCQLFTLTKGGRFYITGIFQILAGLCVMSAAAIYTVRHPEWHLNSDYSYGFAYILAWVAFPLALLSGVIYVILRKRE

Purity

>80% by SDS-PAGE and Coomassie blue staining

Predicted Molecular Mass

44.3 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Activity

This protein was produced in an in vitro wheat germ expression system that should preserve correct conformational folding that is necessary for biological function. While it is possible that this protein could display some level of activity, the functionality of this protein has not been explicitly measured or validated.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human PMP22 GST (N-Term) Protein

SDS-PAGE: Recombinant Human PMP22 GST (N-Term) Protein [H00005376-P01]

SDS-PAGE: Recombinant Human PMP22 GST (N-Term) Protein [H00005376-P01]

SDS-Page: Recombinant Human PMP22 Protein [H00005376-P01] - 12.5% SDS-PAGE Stained with Coomassie Blue.

Formulation, Preparation and Storage

H00005376-P01
Preparation Method in vitro wheat germ expression system
Formulation 50 mM Tris-HCl, 10 mM reduced Glutathione, pH 8.0 in the elution buffer.
Preservative No Preservative
Concentration Please see the vial label for concentration. If unlisted please contact technical services.
Shipping The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at -80C. Avoid freeze-thaw cycles.

Background: PMP22

This gene encodes an integral membrane protein that is a major component of myelin in the peripheral nervous system. Various mutations of this gene are causes of Charcot-Marie-Tooth disease Type IA, Dejerine-Sottas syndrome, and hereditary neuropathy with liability to pressure palsies. Alternative splicing of this gene results in three transcript variants that encode the same protein. [provided by RefSeq]

Alternate Names

CMT1A, CMT1E, GAS3, GAS-3DSS, growth arrest-specific 3, Growth arrest-specific protein 3, HMSNIA, HNPP, MGC20769, peripheral myelin protein 22, PMP-22, Sp110

Gene Symbol

PMP22

Additional PMP22 Products

Product Documents for Recombinant Human PMP22 GST (N-Term) Protein

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Recombinant Human PMP22 GST (N-Term) Protein

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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