Recombinant Human RAR alpha/NR1B1 His Protein

Name: Recombinant Human RAR alpha/NR1B1 His Protein
Brand: Novus Biologicals
SKU: NBP1-98881

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-98881

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Technical Data
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Product Specifications
Scientific Data
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Source

E. coli

Tag

His

Conjugate

Unconjugated

Applications

SDS-PAGE

View all RAR alpha/NR1B1 Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 68-173 of Human RAR alpha/NR1B1

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MSEEIVPSPP SPPPLPRIYK PCFVCQDKSS GYHYGVSACE GCKGFFRRSI QKNMVYTCHR DKNCIINKVT RNRCQYCRLQ KCFEVGMSKE SVRNDRNKKK KEVPKPE

Purity

>95%, by SDS-PAGE

Predicted Molecular Mass

14 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human RAR alpha/NR1B1 His Protein

Recombinant Human RAR alpha/NR1B1 Protein [NBP1-98881] - 3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain.

Formulation, Preparation and Storage

NBP1-98881

Formulation	PBS (pH 7.4), 10% glycerol, 1mM DTT, 0.1M NaCl
Preservative	No Preservative
Concentration	1 mg/ml
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: RAR alpha/NR1B1

Retinoic acid receptors (RAR) belong to the large family of ligand responsive gene regulatory proteins that includes receptors for steroid and thyroid hormones. These proteins contain two highly conserved domains that are involved in determining their DNA and ligand-binding activities. Three isotypes of RARs, alpha, beta, and gamma, are encoded by distinct genetic loci and possess distinct transcriptional properties. Typically, RAR-alpha represses target gene transcription in the absence of hormone, whereas RAR-beta and gamma fail to repress under these conditions. Recombinant human RARalpha, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Long Name

Retinoic Acid Receptor, alpha

Alternate Names

NR1B1, RARA

Gene Symbol

RARA

Additional RAR alpha/NR1B1 Products

Product Documents for Recombinant Human RAR alpha/NR1B1 His Protein

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COA

Product Specific Notices for Recombinant Human RAR alpha/NR1B1 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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