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Recombinant Human RASL12 His Protein

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-51880

Novus Biologicals, part of Bio-Techne
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NBP2-51880-0.1mg
NBP2-51880-0.5mg

Key Product Details

Source

E. coli

Tag

His

Conjugate

Unconjugated

Applications

SDS-PAGE

Product Specifications

Description

A denatured recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-266 of Human RASL12

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSMSSVFGK PRAGSGPQSA PLEVNLAILG RRGAGKSALT VKFLTKRFIS EYDPNLEDTY SSEETVDHQP VHLRVMDTAD LDTPRNCERY LNWAHAFLVV YSVDSRQSFD SSSSYLELLA LHAKETQRSI PALLLGNKLD MAQYRQVTKA EGVALAGRFG CLFFEVSACL DFEHVQHVFH EAVREARREL EKSPLTRPLF ISEERALPHQ APLTARHGLA SCTFNTLSTI NLKEMPTVAQ AKLVTVKSSR AQSKRKAPTL TLLKGFKIF

Purity

>85%, by SDS-PAGE

Predicted Molecular Mass

32.1 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Application Notes

Denatured protein is most likely not the best option for functional studies. It is better suited for Western Blot (WB) or imaging assays.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human RASL12 His Protein

SDS-PAGE: Recombinant Human RASL12 His Protein [NBP2-51880]

SDS-PAGE: Recombinant Human RASL12 His Protein [NBP2-51880]

SDS-Page: RASL12 Recombinant Protein [NBP2-51880] - 15% SDS Page (3 ug)

Formulation, Preparation and Storage

NBP2-51880
Formulation 20 mM Tris-HCl buffer (pH8.0), 10% glycerol
Preservative No Preservative
Concentration 0.5 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: RASL12

Belonging to the small GTPase superfamily/Ras family, RASL12 is localized in the cellular membrane and cytoplasm. RASL12 has many important molecular functions including GTP binding, GTPase activity and nucleotide binding. The main biological function of this gene is to participate in the GTP catabolic process, signal transduction and small GTPase mediated signal transduction. RASL12 interacts with ACVR1, SMAD1, SMAD2, SMAD3 and SMURF2. Documented diseases associated with RASL12 include acute kidney tubular necrosis, intraepithelial neoplasm, retinitis, endometrial cancer, coronary artery disease and Huntington's disease.

Alternate Names

Ras family member Ris, ras-like protein family member 12, RAS-like, family 12, RISRas-like protein Ris

Gene Symbol

RASL12

Additional RASL12 Products

Product Documents for Recombinant Human RASL12 His Protein

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Recombinant Human RASL12 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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