Recombinant Human CD39L2/ENTPD6 Protein, CF
R&D Systems, part of Bio-Techne | Catalog # 4399-EN
Key Product Details
Product Specifications
Source
Chinese Hamster Ovary cell line, CHO-derived human CD39L2/ENTPD6 protein
Lys61-Ser484, with an N-terminal 6-His tag
Accession # O75354
Lys61-Ser484, with an N-terminal 6-His tag
Accession # O75354
Purity
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Endotoxin Level
<1.0 EU per 1 μg of the protein by the LAL method.
N-terminal Sequence Analysis
His
Predicted Molecular Mass
47 kDa
SDS-PAGE
50-55 kDa, reducing conditions
Activity
Measured by its ability to hydrolyze the 5’-phosphate groups from the substrate guanosine-5’-diphosphate (GDP). The orthophosphate product is measured by a Malachite Green Phosphate Detection Kit (Catalog # DY996).
The specific activity is >30,000 pmol/min/µg, as measured under the described conditions.
The specific activity is >30,000 pmol/min/µg, as measured under the described conditions.
Formulation, Preparation and Storage
4399-EN
| Formulation | Supplied as a 0.2 μm filtered solution in Tris, NaCl, CaCl2 and Glycerol. |
| Shipping | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| Stability & Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
|
Background: CD39L2/ENTPD6
Ectonucleoside triphosphate diphosphohydrolase-6 (NTPDase-6) is a secreted nucleoside phosphohydrolase of the CD39 family of enzymes (1). hNTPDase-6 displays a preference for the nucleoside-5’-diphosphates GDP and IDP over CDP and UDP (2). Nucleoside-5’-triphosphates are also hydrolyzed, but at much lower rates. hNTPDase-6 has a broad tissue distribution, its mRNA has been detected in all human tissues tested (1).
References
- Chadwick, B.P. and A.M. Frischauf (1998) Genomics. 50:357.
- Hicks-Berger, C.A. et al. (2000) J. Biol. Chem. 275:34041.
Long Name
Ecto-Nucleoside Triphosphate Diphosphohydrolase 6
Alternate Names
CD39L2, ENTPD6, NTPD3, NTPDase 6
Gene Symbol
ENTPD6
UniProt
Additional CD39L2/ENTPD6 Products
Product Documents for Recombinant Human CD39L2/ENTPD6 Protein, CF
Product Specific Notices for Recombinant Human CD39L2/ENTPD6 Protein, CF
For research use only
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