Recombinant Human Tripeptidyl-peptidase I/TPP1 Protein, CF
R&D Systems, part of Bio-Techne | Catalog # 2237-SE
Key Product Details
Product Specifications
Source
Mouse myeloma cell line, NS0-derived human Tripeptidyl-Peptidase I/TPP1 protein
Met1-Pro563, with a C-terminal 10-His tag
Met1-Pro563, with a C-terminal 10-His tag
Purity
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
Endotoxin Level
<1.0 EU per 1 μg of the protein by the LAL method.
N-terminal Sequence Analysis
Ser20
Predicted Molecular Mass
61 kDa
SDS-PAGE
65-75 kDa, reducing conditions
Activity
Measured by the cleavage of Ala-Ala-Phe-AMC.
The specific activity is >850 pmol/min/μg, as measured under the described conditions.
The specific activity is >850 pmol/min/μg, as measured under the described conditions.
Formulation, Preparation and Storage
2237-SE
| Formulation | Supplied as a 0.2 μm filtered solution in Tris and NaCl. |
| Shipping | The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below. |
| Stability & Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
|
Background: Tripeptidyl-Peptidase I/TPP1
References
- Sleat, D.E. et al. (1997) Science 277:1802.
- Ezaki, J. et al. (1999) J. Neurochem. 72:2573.
- Tomkinson, B. (1999) Trends Biochem. Sci. 24:355.
- Lin, L. et al. (2001) J. Biol. Chem. 276:2249.
- Kida, E. et al. (2001) J. Neuropathol. Exp. Neurol. 60:280.
- Sleat, D.E. et al. (1999) Am. J. Hum. Genet. 64:1511.
Alternate Names
CLN2, LINCL, LPIC, TPP1, TripeptidylPeptidase I
Entrez Gene IDs
1200 (Human)
Gene Symbol
TPP1
UniProt
Additional Tripeptidyl-Peptidase I/TPP1 Products
Product Documents for Recombinant Human Tripeptidyl-peptidase I/TPP1 Protein, CF
Product Specific Notices for Recombinant Human Tripeptidyl-peptidase I/TPP1 Protein, CF
For research use only
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