Recombinant Mouse BTN1A1/Butyrophilin Protein, CF
R&D Systems, part of Bio-Techne | Catalog # 8540-BT
Key Product Details
Product Specifications
Source
Mouse myeloma cell line, NS0-derived mouse BTN1A1/Butyrophilin protein
Ala27-Trp247, with a C-terminal 6-His tag
Ala27-Trp247, with a C-terminal 6-His tag
Purity
>95%, by SDS-PAGE with silver staining.
Endotoxin Level
<0.10 EU per 1 μg of the protein by the LAL method.
N-terminal Sequence Analysis
Ala27
Predicted Molecular Mass
25 kDa
SDS-PAGE
34-42 kDa, reducing conditions
Activity
Measured by its ability to inhibit IL-2 secretion by mouse T cells in the presence of anti-CD3.
The ED50 for this effect is 0.3-1.5 μg/mL.
The ED50 for this effect is 0.3-1.5 μg/mL.
Scientific Data Images for Recombinant Mouse BTN1A1/Butyrophilin Protein, CF
Recombinant Mouse BTN1A1/Butyrophilin Protein Bioactivity
Recombinant Mouse BTN1A1/Butyrophilin (Catalog # 8540-BT) inhibits IL-2 secretion by mouse T cells in the presence of anti-CD3. The ED50 for this effect is 0.3-1.5 μg/mL.Formulation, Preparation and Storage
8540-BT
Formulation | Lyophilized from a 0.2 μm filtered solution in PBS. |
Reconstitution |
Reconstitute at 100 μg/mL in PBS.
|
Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
Stability & Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
|
Background: BTN1A1/Butyrophilin
References
- Abeler-Dorner, L. et al. (2012) Trends Immunol. 33:34.
- Jeong, J. et al. (2009) J. Biol. Chem. 284:22444.
- Vorback, C. et al. (2002) Genes Dev. 16:3223.
- Ogg, S.L. et al. (2004) Proc. Natl. Acad. Sci. USA 101:10084.
- Robenek, H. et al. (2006) Proc. Natl. Acad. Sci. USA 103:10385.
- Sandstrom, A. et al. (2014) Immunity 40:490.
- Arnet, H.A. and Viney, J.L. (2014) Nat.Rev.Immunol.14:559.
- Smith, I.A. et al. (2010) J.Immunol. 184:3514.
- Mana, P. et al. (2004) J.Immunol. 16:489.
Alternate Names
BTN, BTN1A1
Gene Symbol
BTN1A1
UniProt
Additional BTN1A1/Butyrophilin Products
Product Documents for Recombinant Mouse BTN1A1/Butyrophilin Protein, CF
Product Specific Notices for Recombinant Mouse BTN1A1/Butyrophilin Protein, CF
For research use only
Loading...
Loading...
Loading...