Recombinant Human RXR alpha/NR2B1 Protein

Novus Biologicals, part of Bio-Techne | Catalog # NBC1-18416

Novus Biologicals, part of Bio-Techne
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Key Product Details

Source

E. coli

Conjugate

Unconjugated

Applications

SDS-PAGE

View all RXR alpha/NR2B1 Proteins and Enzymes »

Product Specifications

Description

An un-tagged recombinant protein corresponding to the amino acids111-228 of Human RXR alpha/NR2B1

Source: E.coli

Amino Acid Sequence: MLGLNGVLKV PAHPSGNMAS FTKHICAICG DRSSGKHYGV YSCEGCKGFF KRTVRKDLTY TCRDNKDCLI DKRQRNRCQY CRYQKCLAMG MKREAVQEER QRGKDRNENE VESTSSANE

Purity

>95%, by SDS-PAGE

Predicted Molecular Mass

13.5 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human RXR alpha/NR2B1 Protein

SDS-PAGE: Recombinant Human RXR alpha/NR2B1 Protein [NBC1-18416]

SDS-PAGE: Recombinant Human RXR alpha/NR2B1 Protein [NBC1-18416]

SDS-Page: Recombinant Human RXR alpha/NR2B1 Protein [NBC1-18416] - 3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain.

Formulation, Preparation and Storage

NBC1-18416
Formulation 20 mM Tris-HCl buffer (pH 7.5) 0.1 M NaCl, 5mM beta-Mercaptoethanol
Preservative No Preservative
Concentration 1 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: RXR alpha/NR2B1

The retinoid X receptor(RXR) is a pleiotropic nuclear receptor transcription factor that interacts with a variety of nuclear receptor dimeric partner. RXR binds cognate response elements as a homodimer in the presence of its ligand, 9-cis retinoic acid, or as a heterodimer with other members of the nuclear hormone receptor superfamily including retinoic acid receptors(RAR), thyroid hormone receptors(TR), vitamin D receptors and peroxisome proliferators-activated receptors(PPAR). The RXR family includes three difference isoforms ; RXR alpha, beta, gamma. Human RXR alpha gene is localized on 9q34.9 and encodes two major isoforms(RXR alpha1, RXR alpha2). The DNA binding domain of RXR(111-228aa) was over expressed in E.coli and purified by using conventional column chromatography techniques.

Long Name

Retinoid X Receptor, alpha

Alternate Names

NR2B1, RXRA

Gene Symbol

RXRA

Additional RXR alpha/NR2B1 Products

Product Documents for Recombinant Human RXR alpha/NR2B1 Protein

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Recombinant Human RXR alpha/NR2B1 Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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