Recombinant Human SPANXB1 GST (N-Term) Protein

Name: Recombinant Human SPANXB1 GST (N-Term) Protein
Brand: Novus Biologicals
SKU: H00728695-P01

Novus Biologicals, part of Bio-Techne | Catalog # H00728695-P01

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Product Specifications
Scientific Data
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Source

Wheat germ

Tag

GST (N-Term)

Conjugate

Unconjugated

Applications

ELISA, Affinity Purification, Microarray, Western Blot

View all SPANXB1 Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with GST tag at N-terminal corresponding to the amino acids 1-103 of Human SPANXB1

Source: Wheat Germ (in vitro)

Amino Acid Sequence: MGQQSSVRRLKRSVPCESNEANEANEANKTMPETPTGDSDPQPAPKKMKTSESSTILVVRYRRNVKRTSPEELVNDHARENRINPDQMEEEEFIEITTERPKK

Purity

>80% by SDS-PAGE and Coomassie blue staining

Predicted Molecular Mass

37.07 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Activity

This protein was produced in an in vitro wheat germ expression system that should preserve correct conformational folding that is necessary for biological function. While it is possible that this protein could display some level of activity, the functionality of this protein has not been explicitly measured or validated.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human SPANXB1 GST (N-Term) Protein

12.5% SDS-PAGE Stained with Coomassie Blue.

Formulation, Preparation and Storage

H00728695-P01

Preparation Method	in vitro wheat germ expression system
Formulation	50 mM Tris-HCl, 10 mM reduced Glutathione, pH 8.0 in the elution buffer.
Preservative	No Preservative
Concentration	Please see the vial label for concentration. If unlisted please contact technical services.
Shipping	The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at -80C. Avoid freeze-thaw cycles.

Background: SPANXB1

Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family of cancer/testis-associated genes, which are located in a cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene maps to chromosome X in a head-to-tail orientation with SPANX family member B2, which appears to be a duplication of the B1 locus. The SPANXB genes are unique members of this gene family, since they contain an additional 18 nt in their coding region compared to the majority of family members. Although the protein encoded by this gene contains consensus nuclear localization signals, the major site for subcellular localization of expressed protein is in the cytoplasmic droplets of ejaculated spermatozoa. This protein provides a biochemical marker for studying the unique structures in spermatazoa, while attempting to further define its role in spermatogenesis. [provided by RefSeq]

Alternate Names

B1, C, Cancer/testis antigen 11.2, cancer/testis antigen family 11, member 2, CT11.1, CT11.2, CT11.2B1, CT11.3, CT11.4, CTp11, dJ171K16.1, NAP-X, Nuclear-associated protein SPAN-Xb, Nuclear-associated protein SPAN-Xf, SPANX, SPANX family member B/F, SPANX family, member B1, SPANXA, SPAN-Xa, SPANX-A, SPANXB, SPAN-Xb, SPANX-B, SPANXB2, SPANX-C, SPANX-D, SPANXE SPANX family, member E, SPAN-Xf, SPANX-F, SPANXF1, sperm protein associated with the nucleus on the X chromosome B/F, sperm protein associated with the nucleus, X chromosome, family member B1

Gene Symbol

SPANXB1

Additional SPANXB1 Products

Product Documents for Recombinant Human SPANXB1 GST (N-Term) Protein

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COA

SDS

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Product Specific Notices for Recombinant Human SPANXB1 GST (N-Term) Protein

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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