Recombinant Human Tau 441 Active, P301S Mutant, Pre-formed Fibrils Protein [Atto488]
Novus Biologicals, part of Bio-Techne | Catalog # NBP3-14785
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Key Product Details
Conjugate
Atto488 (Excitation= 501 nm, Emission= 523 nm)
Applications
Functional Assay, SDS-PAGE, Western Blot
Product Specifications
Description
A full length recombinant protein of Human Tau 441
Source: E. coli
Uniprot ID: P10636
Amino Acid Sequence: MAEPRQEFEV MEDHAGTYGL GDRKDQGGYT MHQDQEGDTD AGLKESPLQT PTEDGSEEPG SETSDAKSTP TAEDVTAPLV DEGAPGKQAA AQPHTEIPEG TTAEEAGIGD TPSLEDEAAG HVTQARMVSK SKDGTGSDDK KAKGADGKTK IATPRGAAPP GQKGQANATR IPAKTPPAPK TPPSSGEPPK SGDRSGYSSP GSPGTPGSRS RTPSLPTPPT REPKKVAVVR TPPKSPSSAK SRLQTAPVPM PDLKNVKSKI GSTENLKHQP GGGKVQIINK KLDLSNVQSK CGSKDNIKHVSGGGSVQIVY KPVDLSKVTS KCGSLGNIHH KPGGGQVEVK SEKLDFKDRV QSKIGSLDNI THVPGGGNKK IETHKLTFRE NAKAKTDHGA EIVYKSPVVS GDTSPRHLSN VSSTGSIDMV DSPQLATLAD EVSASLAKQG L
Purity
>95%
Activity
Thioflavin T emission curve shows increased fluorescence (correlated to protein fibrillation) when active Tau 441 pre-formed fibrils ATTO-594 are combined with active Tau 441 monomers.
Localization
Cytoplasm, Axolemma, Axolemma Plasma Membrane, Axon, Cell Body, Cell membrane, Cytoplasmic Ribonucleoprotein Granule, Cytoplasmic Side, Cytoskeleton, Cytosol, Dendrite, Growth cone, Microtubule, Microtubule Associated Complex, Neurofibrillary Tangle, Neuronal Cell Body, Nuclear Periphery, Nuclear Speck, Nucleus, Peripheral membrane protein, Plasma Membrane, Tubulin Complex
Protein / Peptide Type
Recombinant Protein
Formulation, Preparation and Storage
NBP3-14785
| Preparation Method | Ion-exchange Purified |
| Formulation | PBS pH 7.4 |
| Preservative | 0.09% Sodium Azide |
| Concentration | Please see the vial label for concentration. If unlisted please contact technical services. |
| Shipping | The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below. |
| Stability & Storage | Store at -80C. Avoid freeze-thaw cycles. |
Background: Tau 441
Alternate Names
MAPT, microtubule-associated protein tau, MTBT1, MTBT2
Gene Symbol
MAPT
Additional Tau 441 Products
Product Specific Notices
Please note that the 200ug and 500ug sizes are sent in 2x100ug and 5x100ug vials, respectively
This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.
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