TEM4 Antibody Blocking Peptide

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-77314PEP

Novus Biologicals, part of Bio-Techne
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NBP1-77314PEP
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Key Product Details

Source

Synthetic

Conjugate

Unconjugated

Applications

Antibody Competition

View all TEM4 Proteins and Enzymes »

Product Specifications

Description

A blocking peptide containing 18 amino acids near the center of human TEM4.

Source: Synthetic

(Accession #: Q96PE2)

Purity

N/A

Application Notes

This peptide is useful as a blocking peptide for NBP1-77314.

For further blocking peptide related protocol, click here.

Protein / Peptide Type

Antibody Blocking Peptide

Formulation, Preparation and Storage

NBP1-77314PEP
Formulation PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin.
Preservative 0.02% Sodium Azide
Concentration 0.2 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at -20C. Avoid freeze-thaw cycles.

Background: TEM4

TEM4 (Tumor endothelial marker 4) is a Rho-specific GEF (guanine-nucleotide exchange factor) with novel structural and regulatory properties and predominant expression in the heart. Rho GTPases, which are activated by specific GEFs, play pivotal roles in several cellular functions. TEM4, encoding a protein containing 1510 amino acids, contains a RhoGEF-specific Dbl homology (DH) domain but lacks their typical pleckstrin homology domain. TEM4 couples tyrosine kinase signals with the activation of the rho/rac GTPases, thus leading to cell differentiation and/or proliferation. Elevated levels of TEM4, TEM5, TEM6, TEM7 and TEM7R were also raised in breast cancer tissues. TEM4 could also prove to be useful as a target, therapeutically.

Alternate Names

164 kDa Rho-specific guanine-nucleotide exchange factor, FLJ90019, KIAA0337P164RHOGEF, p164RhoGEF, p164-RhoGEFRho-specific guanine-nucleotide exchange factor 164 kDa, Rho guanine nucleotide exchange factor (GEF) 17, TEM4rho guanine nucleotide exchange factor 17, Tumor endothelial marker 4

Gene Symbol

ARHGEF17

Additional TEM4 Products

Product Documents for TEM4 Antibody Blocking Peptide

Product Datasheets

Certificate of Analysis

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Product Specific Notices for TEM4 Antibody Blocking Peptide

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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