Recombinant Human TWEAK R/TNFRSF12 Protein
Novus Biologicals, part of Bio-Techne | Catalog # NBP2-35085
Key Product Details
Product Specifications
Description
A single non-glycosylated polypeptide chain containing 53 amino acids corresponding to TWEAK R/TNFRSF12 Source: E. coli
Uniprot ID: Q9NP84
Amino Acid Sequence: EQAPGTAPCS RGSSWSADLD KCMDCASCRA RPHSDFCLGC AAAPPAPFRL LWP
Purity
>95%, by SDS-PAGE and HPLC
Endotoxin Level
Less than 1 EU/ug of TWEAK R/TNFRSF12 as determined by LAL method.
Predicted Molecular Mass
5.6 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Activity
TWEAK R/TNFRSF12 protein is fully biologically active when compared to standard. The ED50 as determined by inhibiting TWEAK-dependent proliferation of human umbilical vein endothelial cells (HUVEC) is less than 30 ng/ml, corresponding to a specific activity of > 3.3 x104 IU/mg, in the presence of 15 ng/ml of rHuTWEAK
Protein / Peptide Type
Recombinant Protein
Scientific Data Images for Recombinant Human TWEAK R/TNFRSF12 Protein
![SDS-PAGE: Recombinant Human TWEAK R/TNFRSF12 Protein [NBP2-35085]](https://resources.bio-techne.com/images/products/Recombinant-Human-TWEAK-R-TNFRSF12-Protein-SDS-Page-NBP2-35085-img0001.jpg "SDS-PAGE: Recombinant Human TWEAK R/TNFRSF12 Protein [NBP2-35085]")
SDS-PAGE: Recombinant Human TWEAK R/TNFRSF12 Protein [NBP2-35085]
SDS-Page: Recombinant Human TWEAK R/TNFRSF12 Protein [NBP2-35085]Formulation, Preparation and Storage
NBP2-35085
| Formulation | Lyophilized from a 0.2 um filtered concentrated solution in PBS, pH 7.4. |
| Preservative | No Preservative |
| Concentration | Lyoph |
| Reconstitution | Recommended to centrifuge prior to opening. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/mL. Apportion stock solutions into working aliquots and store at <-20C. |
| Format | Carrier-Free |
| Shipping | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| Stability & Storage | Store at -20 to -70C as supplied. After reconstitution, store at 2 to 8C for 1 month and at -20 to -70C for long term storage. Avoid repeated freeze-thaw cycles. |
Background: TWEAK R/TNFRSF12
Long Name
TNF-like and Weak Inducer of Apoptosis Receptor
Alternate Names
CD266, Fn14, TNFRSF12, TNFRSF12A, TWEAKR, TWEAK Receptor/TNFRSF12A
Gene Symbol
TNFRSF12A
UniProt
Additional TWEAK R/TNFRSF12 Products
Product Documents for Recombinant Human TWEAK R/TNFRSF12 Protein
Product Specific Notices for Recombinant Human TWEAK R/TNFRSF12 Protein
This lyophilized preparation is stable at 2-8 degrees C, but should be kept at -20 degrees C for long term storage, preferably desiccated. Upon reconstitution, the preparation is most stable at -20 to -80 degrees C, and can be stored for one week at 2-8 degrees C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 degrees C to -80 degrees C. Avoid repeated freeze/thaw cycles.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.
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