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Recombinant Human UBE2R1/CDC34 Protein

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-61361

Novus Biologicals, part of Bio-Techne
Catalog #
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NBP2-61361-1000ug
NBP2-61361-100ug
NBP2-61361-500ug
NBP2-61361-5ug

Key Product Details

Source

E. coli

Conjugate

Unconjugated

Applications

SDS-PAGE

Product Specifications

Description

A single non-glycosylated polypeptide chain containing 236 amino acids corresponding to UBE2R1/CDC34 Source: E. coli

Uniprot ID: P49427

Amino Acid Sequence: MARPLVPSSQ KALLLELKGL QEEPVEGFRV TLVDEGDLYN WEVAIFGPPN TYYEGGYFKA RLKFPIDYPY SPPAFRFLTK MWHPNIYETG DVCISILHPP VDDPQSGELP SERWNPTQNV RTILLSVISL LNEPNTFSPA NVDASVMYRK WKESKGKDRE YTDIIRKQVL GTKVDAERDG VKVPTTLAEY CVKTKAPAPD EGSDLFYDDY YEDGEVEEEA DSCFGDDEDD SGTEES

Purity

>95%, by SDS-PAGE and HPLC

Endotoxin Level

Less than 0.1 EU/ug of UBE2R1/CDC34 as determined by LAL method.

Predicted Molecular Mass

26.7 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Activity

Data is not available.

Protein / Peptide Type

Recombinant Protein

Formulation, Preparation and Storage

NBP2-61361
Formulation A 0.2 um filtered concentrated solution in 50 mM HEPES, pH 7.0, 125 mM NaCl, 10 % Glycerol, 1 mM DTT.
Preservative 5% Trehalose
Concentration Please see the vial label for concentration. If unlisted please contact technical services.
Shipping The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at -20C. Avoid freeze-thaw cycles.

Background: UBE2R1/CDC34

Cdc34 is a ubiquitin conjugating enzyme (UBC) or E2 that has been shown to be essential for the G1 to S phase transition in S. cerevisiae. Human Cdc34 fully complements the budding yeast Cdc34 temperature sensitive mutant phenotype. In egg extracts of the frog Xenopus laevis, Cdc34 has been shown to be required for the onset of DNA replication and appears to function in a multi-protein complex. Also, Cdc34 is highly conserved among vertebrates and is likely to function in a similar manner in all eukaryotes to regulate the start of DNA synthesis.

Alternate Names

Cdc34, UBC3

Gene Symbol

CDC34

Additional UBE2R1/CDC34 Products

Product Documents for Recombinant Human UBE2R1/CDC34 Protein

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Recombinant Human UBE2R1/CDC34 Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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