Recombinant Human WWOX His Protein

Name: Recombinant Human WWOX His Protein
Brand: Novus Biologicals
SKU: NBC1-28766

Novus Biologicals, part of Bio-Techne | Catalog # NBC1-28766

Submit a review

Product Datasheet / COA

100% Guarantee

Technical Data
Citations & Reviews

Product Specifications
Scientific Data
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Source

E. coli

Tag

His

Conjugate

Unconjugated

Applications

SDS-PAGE

View all WWOX Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-234 of Human WWOX

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MAALRYAGLD DTDSEDELPP GWEERTTKDG WVYYANHTEE KTQWEHPKTG KRKRVAGDLP YGWEQETDEN GQVFFVDHIN KRTTYLDPRL AFTVDDNPTK PTTRQRYDGS TTAMEILQGR DFTGKVVVVT GANSGIGFET AKSFALHGAH VILACRNMAR ASEAVSRILE EWQQGAATTV YCAAVPELEG LGGMYFNNCC RCMPSPEAQS EETARTLWAL SERLIQERLG SQSG

Purity

>85%, by SDS-PAGE

Predicted Molecular Mass

28.3 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human WWOX His Protein

SDS-PAGE: Recombinant Human WWOX His Protein [NBC1-28766]

SDS-Page: WWOX Protein [NBC1-28766] - WWOX, 28.3 kDa (254aa), confirmed by MALDI-TOF with a purity of 85% by SDS - PAGE

Formulation, Preparation and Storage

NBC1-28766

Formulation	20 mM Tris-HCl buffer (pH 8.0), 10% glycerol
Preservative	No Preservative
Concentration	1 mg/ml
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: WWOX

WWOX, also known as WW domain containing oxidoreductase, is a proapoptotic protein and a tumor suppressor protein. WWOX is found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This protein may function synergistically with TP53/p53 to control genotoxic stress-induced cell death. It also plays a role in tumor necrosis factor (TNF)-mediated cell death. Recombinant human WWOX protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

Long Name

WW Domain Containing Oxidoreductase

Alternate Names

FOR, FRA16D, SDR41C1, WOX1

Gene Symbol

WWOX

Additional WWOX Products

Product Documents for Recombinant Human WWOX His Protein

Product Datasheets

Download Product Datasheets

COA

Product Specific Notices for Recombinant Human WWOX His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

Citations
Reviews