Recombinant Human XAF1 His Protein

Name: Recombinant Human XAF1 His Protein
Brand: Novus Biologicals
SKU: NBP2-51691

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-51691

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Technical Data
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Product Specifications
Scientific Data
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Source

E. coli

Tag

His

Conjugate

Unconjugated

Applications

SDS-PAGE

View all XAF1 Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1- 125 of Human XAF1

Source: E.coli

Amino Acid Sequence: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMEGD FSVCRNCKRH VVSANFTLHE AYCLRFLVLC PECEEPVPKE TMEEHCKLEH QQVGCTMCQQ SMQKSSLEFH KANECQERPV ECKFCKLDMQ LSKLELHESY CGSRTELCQG CGQFIMHRML A

Purity

>90%, by SDS-PAGE

Predicted Molecular Mass

18.6 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human XAF1 His Protein

SDS-PAGE: Recombinant Human XAF1 His Protein [NBP2-51691]

SDS-Page: XAF1 Recombinant Protein [NBP2-51691] - 15% SDS Page (3 ug)

Formulation, Preparation and Storage

NBP2-51691

Formulation	20mM Tris-HCl buffer (pH 8.0), 30% glycerol, 0.15M NaCl
Preservative	No Preservative
Concentration	1 mg/ml
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: XAF1

X-linked inhibitor of apoptosis (XIAP; MIM 300079) is a potent member of the IAP family. All members of this family possess baculoviral IAP (BIR) repeats, cysteine-rich domains of approximately 80 amino acids that bind and inhibit caspases (e.g., CASP3; MIM 600636). XIAP has 3 BIR domains and a C-terminal RING zinc finger that possesses E3 ubiquitin ligase (see MIM 601623) activity. XAF1 antagonizes the anticaspase activity of XIAP and may be important in mediating apoptosis resistance in cancer cells (Liston et al., 2001 [PubMed 11175744]).[supplied by OMIM]

Alternate Names

BIRC4-binding protein, BIRC4BPBIRC4 binding protein, HSXIAPAF1, XIAP associated factor 1, XIAPAF1XIAP-associated factor 1

Gene Symbol

XAF1

Additional XAF1 Products

Product Documents for Recombinant Human XAF1 His Protein

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COA

Product Specific Notices for Recombinant Human XAF1 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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