2-Chloro-N⁶-cyclopentyladenosine

Name: 2-Chloro-N 6 -cyclopentyladenosine
Brand: Tocris Bioscience
SKU: 1705

Tocris Bioscience, part of Bio-Techne | Catalog # 1705

Citations (23)

COA / SDS

Potent and selective A1 agonist

Key Product Details

Description:	Potent and selective A₁ agonist
Alternative Names:	CCPA
Chemical Name:	2-Chloro-N-cyclopentyladenosine
Purity:	≥98% (HPLC)
Molecular Weight:	369.81

View Full Technical Details for 2-Chloro-N⁶-cyclopentyladenosine

Technical Data
Citations

Biological Activity for 2-Chloro-N⁶-cyclopentyladenosine

2-Chloro-N⁶-cyclopentyladenosine is a potent and selective adenosine A₁ receptor agonist (K_i values are 0.8, 2300 and 42 nM for human A₁, A_2A and A₃ receptors respectively; EC₅₀ = 18800 nM for hA_2B). Centrally active following systemic administration in vivo.

Compound Libraries for 2-Chloro-N⁶-cyclopentyladenosine

2-Chloro-N⁶-cyclopentyladenosine is also offered as part of the Tocriscreen 2.0 Max. Find out more about compound libraries available from Tocris.

Technical Data for 2-Chloro-N⁶-cyclopentyladenosine

M. Wt	369.81
Formula	C₁₅H₂₀ClN₅O₄
Storage	Desiccate at RT
Purity	≥98% (HPLC)
CAS Number	37739-05-2
PubChem ID	123807
InChi Key	XSMYYYQVWPZWIZ-IDTAVKCVSA-N
Smiles	O[C@@H]1[C@@H](CO)O[C@@H](N(C=N4)C2=C4C(NC3CCCC3)=NC(Cl)=N2)[C@@H]1O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for 2-Chloro-N⁶-cyclopentyladenosine

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
	DMSO	36.98	100
	ethanol	36.98	100

Preparing Stock Solutions for 2-Chloro-N⁶-cyclopentyladenosine

The following data is based on the product molecular weight 369.81.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.70 mL	13.52 mL	27.04 mL
5 mM	0.54 mL	2.70 mL	5.41 mL
10 mM	0.27 mL	1.35 mL	2.70 mL
50 mM	0.05 mL	0.27 mL	0.54 mL

Molarity Calculator

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Dilution Calculator

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Reconstitution Calculator

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References for 2-Chloro-N⁶-cyclopentyladenosine

References are publications that support the biological activity of the product.

Monopoli Pharmacology of the highly selective A₁ adenosine receptor agonist 2-chloro-N⁶-cyclopentyladenosine. Arzneimittelforschung 1994 PMID: 7848348
Klotz Adenosine receptors and their ligands. Naunyn Schmiedebergs Arch.Pharmacol. 2000 PMID: 11111832
Lohse 2-Chloro-N⁶-cyclopentyladenosine: a highly selective agonist at A₁ adenosine receptors. Naunyn Schmiedebergs Arch.Pharmacol. 1988 PMID: 3216901
Concas Anticonvulsant doses of 2-chloro-N⁶-cyclopentyladenosine, an adenosine A₁ receptor agonist, reduce GABAergic transmission in different areas of the mouse brain. J.Pharmacol.Exp.Ther. 1993 PMID: 8246158

2-Chloro-N⁶-cyclopentyladenosine

Tocris Bioscience, part of Bio-Techne | Catalog # 1705

Key Product Details

Biological Activity for 2-Chloro-N⁶-cyclopentyladenosine

Compound Libraries for 2-Chloro-N⁶-cyclopentyladenosine

Technical Data for 2-Chloro-N⁶-cyclopentyladenosine

Solubility for 2-Chloro-N⁶-cyclopentyladenosine

Preparing Stock Solutions for 2-Chloro-N⁶-cyclopentyladenosine

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for 2-Chloro-N⁶-cyclopentyladenosine

Product Documents for 2-Chloro-N⁶-cyclopentyladenosine

COA

Certificate of Analysis

SDS

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2-Chloro-N6-cyclopentyladenosine

Tocris Bioscience, part of Bio-Techne | Catalog # 1705

Key Product Details

Biological Activity for 2-Chloro-N6-cyclopentyladenosine

Compound Libraries for 2-Chloro-N6-cyclopentyladenosine

Technical Data for 2-Chloro-N6-cyclopentyladenosine

Solubility for 2-Chloro-N6-cyclopentyladenosine

Preparing Stock Solutions for 2-Chloro-N6-cyclopentyladenosine

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for 2-Chloro-N6-cyclopentyladenosine

Product Documents for 2-Chloro-N6-cyclopentyladenosine

COA

Certificate of Analysis

SDS

2-Chloro-N⁶-cyclopentyladenosine

Biological Activity for 2-Chloro-N⁶-cyclopentyladenosine

Compound Libraries for 2-Chloro-N⁶-cyclopentyladenosine

Technical Data for 2-Chloro-N⁶-cyclopentyladenosine

Solubility for 2-Chloro-N⁶-cyclopentyladenosine

Preparing Stock Solutions for 2-Chloro-N⁶-cyclopentyladenosine

References for 2-Chloro-N⁶-cyclopentyladenosine

Product Documents for 2-Chloro-N⁶-cyclopentyladenosine