2-ThioUTP tetrasodium salt

Name: 2-ThioUTP tetrasodium salt
Brand: Tocris Bioscience
SKU: 3280

Tocris Bioscience, part of Bio-Techne | Catalog # 3280

Citations (5)

COA / SDS

Potent and selective P2Y2 agonist

Key Product Details

Description:	Potent and selective P2Y₂ agonist
Chemical Name:	2-Thiouridine 5'-triphosphate tetrasodium salt
Purity:	≥95% (HPLC)
Molecular Weight:	588.13

View Full Technical Details for 2-ThioUTP tetrasodium salt

Technical Data
Citations

Biological Activity for 2-ThioUTP tetrasodium salt

2-ThioUTP tetrasodium salt is a potent and selective P2Y₂ agonist (EC₅₀ values are 0.035, 0.35 and 1.5 μM for hP2Y₂, hP2Y₄ and hP2Y₆ receptors respectively).

Technical Data for 2-ThioUTP tetrasodium salt

M. Wt	588.13
Formula	C₉H₁₁N₂Na₄O₁₄P₃S
Storage	Store at -20°C
Purity	≥95% (HPLC)
CAS Number	1343364-70-4
PubChem ID	54591573
InChi Key	QCBCNKBBEOQRRB-ODQFIEKDSA-J
Smiles	[Na+].[Na+].[Na+].[Na+].O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])(=O)OP([O-])(=O)OP([O-])([O-])=O)N1C=CC(=O)NC1=S

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for 2-ThioUTP tetrasodium salt

Solubility

Soluble in water (supplied pre-dissolved at a concentration of 10mM)

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References for 2-ThioUTP tetrasodium salt

References are publications that support the biological activity of the product.

Ko Synthesis and potency of novel uracil nucleotides and derivatives as P2Y₂ and P2Y₆ receptor agonists. Bioorg.Med.Chem. 2008 PMID: 18514530
El-Tayeb Synthesis and structure-activity relationships of uracil nucleotide derivatives and analogues as agonists at human P2Y₂, P2Y₄ and P2Y₆ receptors. J.Med.Chem. 2006 PMID: 17125260