4-Acetyl-1,1-dimethylpiperazinium iodide

Name: 4-Acetyl-1,1-dimethylpiperazinium iodide
Brand: Tocris Bioscience
SKU: 0352

Tocris Bioscience, part of Bio-Techne | Catalog # 0352

COA / SDS

nAChR agonist

Discontinued Product

0352 has been discontinued. View all Additional Nicotinic Receptor Agonists products.

Key Product Details

Description:	nAChR agonist
Molecular Weight:	284.14

View Full Technical Details for 4-Acetyl-1,1-dimethylpiperazinium iodide

Technical Data
Citations

Biological Activity for 4-Acetyl-1,1-dimethylpiperazinium iodide

4-Acetyl-1,1-dimethylpiperazinium iodide is a structural analog of acetylcholine that acts as a nicotinic agonist (K_i = 29.9 nM at α4β2). Upregulates the number of α4β2 binding sites in M10 cells in vitro by 440%.

Technical Data for 4-Acetyl-1,1-dimethylpiperazinium iodide

M. Wt	284.14
Formula	C₈H₁₇IN₂O
Storage	Store at RT
CAS Number	75667-84-4
PubChem ID	5311072
InChi Key	VXBLRKDEHGKPAC-UHFFFAOYSA-M
Smiles	C[N+]1(C)CCN(CC1)C(=O)C.[I-]

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for 4-Acetyl-1,1-dimethylpiperazinium iodide

References are publications that support the biological activity of the product.

Spivak Structural and electronic requirements for potent agonists at a nicotinic receptor. Eur.J.Pharmacol. 1986 PMID: 3485051
Warpman Regulation of nicotinic receptor subtypes following chronic nicotinic agonist exposure in M10 and SH-SY5Y neuroblastoma cells. J.Neurochem. 1998 PMID: 9572289
Spivak Binding of semirigid nicotinic agonists to nicotinic and muscarinic receptors. Mol.Pharmacol. 1988 PMID: 2747625

4-Acetyl-1,1-dimethylpiperazinium iodide

Tocris Bioscience, part of Bio-Techne | Catalog # 0352

Key Product Details

Biological Activity for 4-Acetyl-1,1-dimethylpiperazinium iodide

Technical Data for 4-Acetyl-1,1-dimethylpiperazinium iodide

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for 4-Acetyl-1,1-dimethylpiperazinium iodide

Product Documents for 4-Acetyl-1,1-dimethylpiperazinium iodide

COA

Certificate of Analysis

SDS

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