Ac₄GalN6yne

Name: Ac 4 GalN6yne
Brand: Tocris Bioscience
SKU: 7932

Tocris Bioscience, part of Bio-Techne | Catalog # 7932

COA / SDS

Alkyne containing monosaccharide building block; used in BOCTAG

Key Product Details

Description:	Alkyne containing monosaccharide building block; used in BOCTAG
Chemical Name:	2-Deoxy-2-[(1-oxo-5-hexyn-1-yl)amino]-D-galactopyranose-1,3,4,6-tetraacetate
Purity:	≥95% (HPLC)
Molecular Weight:	441.43

View Full Technical Details for Ac₄GalN6yne

Technical Data
Citations

Biological Activity for Ac₄GalN6yne

Ac₄GalN6yne is a cell-permeable alkyne-containing monosaccharide building block. It can be used in Bio-Orthogonal Cell-specific Tagging of Glycoproteins (BOCTAG) technique. In this strategy, cells carrying an artificial biosynthetic pathway (B. longum NahK and mut-AGX1) can generate alkyne-tagged UDP-GalN6yne, that are then used by glycosyltransferases to chemically tag the glycoproteome. Ac₄GalN6yne can be used for bioorthogonal labelling in vitro and mouse models.

Technical Data for Ac₄GalN6yne

M. Wt	441.43
Formula	C₂₀H₂₇NO₁₀
Storage	Store at -20°C
Purity	≥95% (HPLC)
InChi Key	RWQXKPQZNDMFQH-FIBJEGPVSA-N
Smiles	O=C(N[C@@H]1[C@H]([C@H]([C@H](OC1OC(C)=O)COC(C)=O)OC(C)=O)OC(C)=O)CCCC#C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Ac₄GalN6yne

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	DMSO	8.83	20 with gentle warming

Preparing Stock Solutions for Ac₄GalN6yne

The following data is based on the product molecular weight 441.43.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.2 mM	11.33 mL	56.63 mL	113.27 mL
1 mM	2.27 mL	11.33 mL	22.65 mL
2 mM	1.13 mL	5.66 mL	11.33 mL
10 mM	0.23 mL	1.13 mL	2.27 mL

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References for Ac₄GalN6yne

References are publications that support the biological activity of the product.

Cioce Cell-specific bioorthogonal tagging of glycoproteins. Nat.Commun. 2022 PMID: 36284108

Ac₄GalN6yne

Tocris Bioscience, part of Bio-Techne | Catalog # 7932

Key Product Details

Biological Activity for Ac₄GalN6yne

Technical Data for Ac₄GalN6yne

Solubility for Ac₄GalN6yne

Preparing Stock Solutions for Ac₄GalN6yne

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for Ac₄GalN6yne

Product Documents for Ac₄GalN6yne

COA

Certificate of Analysis

SDS

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Ac4GalN6yne

Tocris Bioscience, part of Bio-Techne | Catalog # 7932

Key Product Details

Biological Activity for Ac4GalN6yne

Technical Data for Ac4GalN6yne

Solubility for Ac4GalN6yne

Preparing Stock Solutions for Ac4GalN6yne

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for Ac4GalN6yne

Product Documents for Ac4GalN6yne

COA

Certificate of Analysis

SDS

Ac₄GalN6yne

Biological Activity for Ac₄GalN6yne

Technical Data for Ac₄GalN6yne

Solubility for Ac₄GalN6yne

Preparing Stock Solutions for Ac₄GalN6yne

References for Ac₄GalN6yne

Product Documents for Ac₄GalN6yne