α-Estradiol

Name: α-Estradiol
Brand: Tocris Bioscience
SKU: 2823

Tocris Bioscience, part of Bio-Techne | Catalog # 2823

Citations (1)

COA / SDS

Endogenous estrogen receptor agonist

Key Product Details

Chemical Name:	(17α)-Estra-1,3,5(10)-triene-3,17-diol
Purity:	≥97%
Molecular Weight:	272.38 kDa

View Full Technical Details for α-Estradiol

Technical Data
Citations

Biological Activity for α-Estradiol

α-Estradiol is an endogenous estrogen receptor ligand (K_i values are 0.2 and 1.2 nM for ERα and ERβ receptors respectively).

β-Estradiol also available.

Technical Data for α-Estradiol

M. Wt	272.38 kDa
Formula	C₁₈H₂₄O₂
Storage	Store at RT
Purity	≥97%
CAS Number	57-91-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for α-Estradiol

Solubility

Soluble Soluble to 100 mM in DMSO and to 100 mM in ethanol

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References for α-Estradiol

References are publications that support the biological activity of the product.

Kuiper et al. Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors α and β. Endocrinology, 1997;138:863 PMID: 9048584
Toran-Allerand et al. ER-X: a novel, plasma membrane-associated, putative estrogen receptor that is regulated during development and after ischemic brain injury. J.Neurosci., 2002;22:8391 PMID: 12351713