Angiotensin (1-7)

Name: Angiotensin (1-7)
Brand: Tocris Bioscience
SKU: 1562

Tocris Bioscience, part of Bio-Techne | Catalog # 1562

Citations (8)

COA / SDS

Vasorelaxant peptide

Key Product Details

Description:	Vasorelaxant peptide
Alternative Names:	[Ile⁵]Angiotensin I (1-7),Ang-(1-7)
Purity:	≥95% (HPLC)
Molecular Weight:	899

View Full Technical Details for Angiotensin (1-7)

Technical Data
Citations

Biological Activity for Angiotensin (1-7)

Angiotensin (1-7) is an endogenous peptide fragment. Induces vasorelaxation through release of NO and prostaglandins, perhaps through activation of a non-AT₁, non-AT₂ receptor, Mas. Counteracts the vasoconstrictive and proliferative effects of angiotensin II and stimulates vasopressin (anti-diuretic hormone) release in vivo.

Technical Data for Angiotensin (1-7)

M. Wt	899
Formula	C₄₁H₆₂N₁₂O₁₁
Single Letter Sequence	DRVYIHP
Storage	Store at -20°C
Purity	≥95% (HPLC)
CAS Number	51833-78-4
PubChem ID	123805
InChi Key	PVHLMTREZMEJCG-GDTLVBQBSA-N
Smiles	[H]N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N1CCC[C@H]1C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Angiotensin (1-7)

Solubility

Soluble to 1mg/ml in water

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt*

g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

References for Angiotensin (1-7)

References are publications that support the biological activity of the product.

Santos Angiotensin-(1-7): an update. Regul.Pept. 2000 PMID: 10967201
Santos Angiotensin-(1-7) is an endogenous ligand for the G protein-coupled receptor Mas. Proc.Natl.Acad.Sci.U.S.A. 2003 PMID: 12829792
Lemos Angiotensin-(1-7) is involved in the endothelium-dependent modulation of phenylephrine-induced contraction in the aorta of mRen-2 transgenic rats. Br.J.Pharmacol. 2002 PMID: 11934815