Angiotensin I (human, mouse, rat)

Name: Angiotensin I (human, mouse, rat)
Brand: Tocris Bioscience
SKU: 1563

Tocris Bioscience, part of Bio-Techne | Catalog # 1563

COA / SDS

Endogenous precursor to angiotensin II (Cat. No. 1158)

Key Product Details

Description:	Endogenous precursor to angiotensin II (Cat. No. 1158)
Purity:	≥95% (HPLC)
Molecular Weight:	1296.5

View Full Technical Details for Angiotensin I (human, mouse, rat)

Technical Data
Citations

Biological Activity for Angiotensin I (human, mouse, rat)

Angiotensin I (human, mouse, rat) is an endogenous peptide substrate for angiotensin converting enzyme (ACE) and ACE2; precursor to the vasoconstrictor peptide angiotensin II (Cat. No. 1158).

Technical Data for Angiotensin I (human, mouse, rat)

M. Wt	1296.5
Formula	C₆₂H₈₉N₁₇O₁₄
Single Letter Sequence	DRVYIHPFHL
Storage	Store at -20°C
Purity	≥95% (HPLC)
CAS Number	484-42-4
PubChem ID	3081372
InChi Key	ORWYRWWVDCYOMK-HBZPZAIKSA-N
Smiles	[H]N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC(C)C)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Angiotensin I (human, mouse, rat)

Solubility

Soluble to 1mg/ml in water

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References for Angiotensin I (human, mouse, rat)

References are publications that support the biological activity of the product.

Erdos and Skidgel Renal metabolism of angiotensin I and II. Kidney Int.Suppl. 1990 PMID: 2175370
Manabe Endothelium-dependent contractions induced by angiotensin I and angiotensin II in canine cerebral artery. J.Pharmacol.Exp.Ther. 1989 PMID: 2795464
Erdo Conversion of angiotensin I to angiotensin II. Am.J.Med. 1976 PMID: 190881