BAY 677

Name: BAY 677
Brand: Tocris Bioscience
SKU: 6389

Tocris Bioscience, part of Bio-Techne | Catalog # 6389

COA / SDS

Inactive control for BAY 678 (Cat.No.5706)

Discontinued Product

6389 has been discontinued. View all Synthetic Elastase Inhibitors products.

Key Product Details

Description:	Inactive control for BAY 678 (Cat.No.5706)
Chemical Name:	5-[(4S)-5-Acetyl-1,2,3,4-tetrahydro-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-4-pyrimidinyl]-2-pyridinecarbonitrile
Purity:	≥98% (HPLC)
Molecular Weight:	400.35

View Full Technical Details for BAY 677

Technical Data
Citations

Biological Activity for BAY 677

BAY 677 is an inactive control for BAY 678 (Cat.No.5706).

Licensing Information

This probe is supplied in conjunction with the Structural Genomics Consortium. For further characterization details, please visit the BAY 678 probe summary on the SGC website.

Technical Data for BAY 677

M. Wt	400.35
Formula	C₂₀H₁₅F₃N₄O₂
Storage	Store at -20°C
Purity	≥98% (HPLC)
CAS Number	2117404-84-7
PubChem ID	68944900
InChi Key	PGIVGIFOWOVINL-SFHVURJKSA-N
Smiles	CC(C1=C(N(C2=CC(C(F)(F)F)=CC=C2)C(N[C@H]1C3=CN=C(C#N)C=C3)=O)C)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt*

g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

References for BAY 677

References are publications that support the biological activity of the product.

von Nussbaum Freezing the bioactive conformation to boost potency: The identification of BAY 85-8501, a selective and potent inhibitor of human neutrophil elastase for pulmonary diseases. ChemMedChem 2015 PMID: 26083237