Beraprost sodium

Name: Beraprost sodium
Brand: Tocris Bioscience
SKU: 4180

Tocris Bioscience, part of Bio-Techne | Catalog # 4180

Citations (3)

COA / SDS

Potent prostacyclin IP receptor agonist

Discontinued Product

4180 has been discontinued. View all Prostanoid Receptor Agonists products.

Key Product Details

Description:	Potent prostacyclin IP receptor agonist
Chemical Name:	rel-(1R,2R,3aS,8bS)-2,3,3a,8b-Tetrahydro-2-hydroxy-1-[(1E,3S)-3-hydroxy-4-methyl-1-octen-6-yn-1-yl)-1H-cyclopenta[b]benzofuran-5-butanoic acid sodium salt
Purity:	≥98% (HPLC)
Molecular Weight:	420.47

View Full Technical Details for Beraprost sodium

Technical Data
Citations

Biological Activity for Beraprost sodium

Beraprost sodium is a potent IP receptor agonist; analog of Epoprostenol (Cat. No. 2989). Potently inhibits ADP-induced platelet aggregation and P-selectin expression in vitro (pIC₅₀ values are 8.26 and 8.56, respectively). Also increases vasodilation and reduces pulmonary hypertension in vivo. Orally active.

Technical Data for Beraprost sodium

M. Wt	420.47
Formula	C₂₄H₂₉NaO₅
Storage	Store at -20°C
Purity	≥98% (HPLC)
CAS Number	496807-11-5
PubChem ID	23663404
InChi Key	JLHRLDZCMGGIKW-OQNJEIHKSA-M
Smiles	O[C@@H]1C[C@H]2[C@H](C(C=CC=C3CCCC(O[Na])=O)=C3O2)[C@H]1/C=C/[C@@H](O)C(C)CC#CC.O[C@H]4C[C@@H]5[C@@H](C(C=CC=C6CCCC(O[Na])=O)=C6O5)[C@@H]4/C=C/[C@H](O)C(C)CC#CC

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt*

g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

References for Beraprost sodium

References are publications that support the biological activity of the product.

Saito Effects of beraprost sodium (a PGI2 derivative) on chronic hypoxic pulmonary hypertension in the rat. Nihon Kyobu Shikkan Gakkai Zasshi. 1995 PMID: 7609334
Miyamoto Effects of TRA-418, a novel TP-receptor antagonist, and IP-receptor agonist, on human platelet activation and aggregation. Br.J.Pharmacol. 2003 PMID: 14504133

Beraprost sodium

Tocris Bioscience, part of Bio-Techne | Catalog # 4180

Key Product Details

Biological Activity for Beraprost sodium

Technical Data for Beraprost sodium

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for Beraprost sodium

Product Documents for Beraprost sodium

COA

Certificate of Analysis

SDS

CONTACT INFORMATION

Stay Connected