Betaxolol hydrochloride

Name: Betaxolol hydrochloride
Brand: Tocris Bioscience
SKU: 0906

Tocris Bioscience, part of Bio-Techne | Catalog # 0906

Citations (5)

COA / SDS

Selective β1 antagonist

Key Product Details

Description:	Selective β₁ antagonist
Chemical Name:	1-[4-[2-(Cyclopropylmethoxy)ethyl]phenoxy]-3-isopropylamino-2-propanol hydrochloride
Purity:	≥99% (HPLC)
Molecular Weight:	343.89

View Full Technical Details for Betaxolol hydrochloride

Technical Data
Citations

Biological Activity for Betaxolol hydrochloride

Betaxolol hydrochloride is a selective β₁-adrenoceptor antagonist.

Technical Data for Betaxolol hydrochloride

M. Wt	343.89
Formula	C₁₈H₂₉NO₃.HCl
Storage	Store at RT
Purity	≥99% (HPLC)
CAS Number	63659-19-8
PubChem ID	107952
InChi Key	CHDPSNLJFOQTRK-UHFFFAOYSA-N
Smiles	Cl.CC(C)NCC(O)COC1=CC=C(CCOCC2CC2)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Betaxolol hydrochloride

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	water	17.19	50

Preparing Stock Solutions for Betaxolol hydrochloride

The following data is based on the product molecular weight 343.89.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.5 mM	5.82 mL	29.08 mL	58.16 mL
2.5 mM	1.16 mL	5.82 mL	11.63 mL
5 mM	0.58 mL	2.91 mL	5.82 mL
25 mM	0.12 mL	0.58 mL	1.16 mL

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Reconstitution Calculator

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References for Betaxolol hydrochloride

References are publications that support the biological activity of the product.

Satoh The affinity of betaxolol, a β₁-adrenoceptor-selective blocking agent, for β-adrenoceptors in the bovine trachea and heart Br.J.Pharmacol. 1993 PMID: 8383566
Setoguchi Inhibitory action of betaxolol, a β₁-selective adrenoceptor antagonist, on voltage-dependent calcium channels in guinea pig artery and vein. Br.J.Pharmacol. 1995 PMID: 7647977
Beresford and Heel Betaxolol. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy in hypertension. Drugs 1986 PMID: 2866947